Uterine leiomyosarcoma: A review of the literature and update on management options

ME Roberts, JT Aynardi, CS Chu - Gynecologic Oncology, 2018 - Elsevier
Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely
aggressive malignancy associated with a poor overall prognosis. Women affected may vary …

Ovarian, uterine, and cervical cancer patients with distant metastases at diagnosis: most common locations and outcomes

AB Gardner, LM Charo, AK Mann, DS Kapp… - Clinical & experimental …, 2020 - Springer
To determine the location patterns of distant metastases at initial staging and outcomes of
ovarian, uterine, and cervical cancer patients. Data were obtained from the SEER database …

[HTML][HTML] Leiomyosarcoma: a rare soft tissue cancer arising from multiple organs

Z Singh - Journal of cancer research and practice, 2018 - Elsevier
Leiomyosarcoma (LMS), a smooth muscle connective tissue tumor, is a rare form of cancer
which accounts for 5–10% of soft tissue sarcomas. This type of cancer is highly …

Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma

Y Nagao, A Yokoi, K Yoshida, M Sugiyama… - Pharmacological …, 2023 - Elsevier
Uterine leiomyosarcoma (ULMS) is a malignant stromal tumor arising from the myometrium
with a poor prognosis and very limited response to current chemotherapy. This study aimed …

Phoyunnanin E inhibits migration of non-small cell lung cancer cells via suppression of epithelial-to-mesenchymal transition and integrin αv and integrin β3

N Petpiroon, B Sritularak, P Chanvorachote - BMC complementary and …, 2017 - Springer
Background The conversion of the epithelial phenotype of cancer cells into cells with a
mesenchymal phenotype-so-called epithelial–mesenchymal transition (EMT)-has been …

Impact of perioperative characteristics on the recurrence risk and survival of patients with uterine leiomyosarcoma

M Gracia, Y Yildirim, R Macuks… - … of Gynecology & …, 2023 - Wiley Online Library
Objectives To analyze the impact of perioperative characteristics on the risk of recurrence in
patients with uterine leiomyosarcomas. Methods A sub‐analysis of the SARComa of the …

A phase II randomised (calibrated design) study on the activity of the single-agent trabectedin in metastatic or locally relapsed uterine leiomyosarcoma

A Gadducci, F Grosso, G Scambia… - British Journal of …, 2018 - nature.com
Background Patients with recurrent/metastatic uterine leiomyosarcoma (U-LMS) have a
dismal prognosis. This phase II study aims to evaluate trabectedin efficacy and safety in …

Immune checkpoint blockade as a potential therapeutic target in non-small cell lung cancer

J Yang, J Chen, J Wei, X Liu… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: The recent emergence of immune checkpoint blockade therapy and the
progression of immunobiology in cancer have spurred an increasing interest in the …

Primary intracranial leiomyosarcoma secondary to glioblastoma: case report and literature review

L Zhao, Y Jiang, Y Wang, Y Bai, Y Sun, Y Li - Frontiers in oncology, 2021 - frontiersin.org
Background Leiomyosarcoma is a highly malignant soft-tissue sarcoma with a poor
prognosis. In recent years, treatment for leiomyosarcoma has not shown much progress …

Lung metastases regression with increased CD8+ T lymphocyte infiltration following preoperative spinal embolization and total en bloc spondylectomy using tumor …

N Yonezawa, H Murakami, A Sangsin… - European Spine …, 2019 - Springer
Purpose To report systemic immunological enhancement following preoperative spinal
embolization and total en bloc spondylectomy (TES) using tumor-bearing frozen autograft in …