G Vashchenko, RTA MacGillivray - Nutrients, 2013 - mdpi.com
Multi-copper oxidases (MCOs) are a small group of enzymes that oxidize their substrate with the concomitant reduction of dioxygen to two water molecules. Generally, multi-copper …
The mammalian multicopper ferroxidases (MCFs) ceruloplasmin (CP), hephaestin (HEPH) and zyklopen (ZP) comprise a family of conserved enzymes that are essential for body iron …
LA Lambert - Biochimica et Biophysica Acta (BBA)-General Subjects, 2012 - Elsevier
BACKGROUND: In vertebrates, serum transferrins are essential iron transporters that have bind and release Fe (III) in response to receptor binding and changes in pH. Some family …
NL Chepelev, WG Willmore - Free Radical Biology and Medicine, 2011 - Elsevier
Constituting an integral part of a heme's porphyrin ring, iron is essential for supplying cells and tissues with oxygen. Given tight links between oxygen delivery and iron availability, it is …
Lactoferrin (LF) is an iron-binding glycoprotein that is composed of the transferrin family and is predominantly found in the products of the exocrine glands located in the gateways of the …
G Ianiro, L Rosa, MC Bonaccorsi di Patti, P Valenti… - Biometals, 2023 - Springer
Iron is by far the most widespread and essential transition metal, possessing crucial biological functions for living systems. Despite chemical advantages, iron biology has forced …
Ceruloplasmin (CP) is a mammalian blood plasma ferroxidase. More than 95% of the copper found in plasma is carried by this protein, which is a member of the multicopper …
ET Zakharova, AV Sokolov, NN Pavlichenko… - Biometals, 2018 - Springer
Among the properties of lactoferrin (LF) are bactericidal, antianemic, immunomodulatory, antitumour, antiphlogistic effects. Previously we demonstrated its capacity to stabilize in vivo …
AV Sokolov, ET Zakahrova, VA Kostevich… - Biometals, 2014 - Springer
Copper-containing plasma protein ceruloplasmin (Cp) forms a complex with lactoferrin (Lf), an iron-binding protein, and with the heme-containing myeloperoxidase (Mpo). In case of …