Overcoming skin barriers through advanced transdermal drug delivery approaches

V Phatale, KK Vaiphei, S Jha, D Patil, M Agrawal… - Journal of controlled …, 2022 - Elsevier
Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …

Chronic inflammatory diseases, anti-inflammatory agents and their delivery nanosystems

D Placha, J Jampilek - Pharmaceutics, 2021 - mdpi.com
Inflammatory diseases, whether caused by excessive stress on certain tissues/parts of the
body or arising from infections accompanying autoimmune or secondary diseases, have …

A novel drug combination of mangiferin and cinnamic acid alleviates rheumatoid arthritis by inhibiting TLR4/NFκB/NLRP3 activation-induced pyroptosis

W Li, K Wang, Y Liu, H Wu, Y He, C Li, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Growing evidence shows that Baihu-Guizhi decoction (BHGZD), a traditional Chinese
medicine (TCM)-originated disease-modifying anti-rheumatic prescription, may exert a …

Polymeric microneedle-mediated transdermal delivery of melittin for rheumatoid arthritis treatment

G Du, P He, J Zhao, C He, M Jiang, Z Zhang… - Journal of Controlled …, 2021 - Elsevier
Transdermal drug delivery systems for rheumatoid arthritis (RA) have been receiving
increasing attention as they can potentially overcome drawbacks which exist in traditional …

Albendazole nanocrystal-based dissolving microneedles with improved pharmacokinetic performance for enhanced treatment of cystic echinococcosis

AD Permana, AJ Paredes, FV Zanutto… - … Applied Materials & …, 2021 - ACS Publications
Cystic echinococcosis (CE) is a zoonosis caused by Echinococcus spp., affecting both
humans and animals' lives. Current treatment of CE by oral administration of albendazole …

Hyaluronan-modified transfersomes based hydrogel for enhanced transdermal delivery of indomethacin

M Yuan, J Niu, Q Xiao, H Ya, Y Zhang, Y Fan, L Li… - Drug …, 2022 - Taylor & Francis
Hyaluronic acid (HA), as a hygroscopic and biocompatible molecule, has displayed unique
permeation enhancement in transdermal delivery systems. Hence, indomethacin (IND) was …

Hydrogel containing solid lipid nanoparticles loaded with argan oil and simvastatin: Preparation, in vitro and ex vivo assessment

MFA Khan, A Ur. Rehman, H Howari, A Alhodaib… - Gels, 2022 - mdpi.com
Transdermal hydrogels have the potential to improve therapeutic outcomes via enhancing
bioavailability and reducing toxicity associated with oral delivery. The goal of the present …

Quality by design for sumatriptan loaded nano-ethosomal mucoadhesive gel for the therapeutic management of nitroglycerin induced migraine

U Shafique, F ud Din, S Sohail, S Batool… - International Journal of …, 2023 - Elsevier
Migraine is a progressive neurological condition often accompanied by nausea and
vomiting. Various drugs have recently been used in the treatment of migraine, including …

Recent advances on transdermal delivery systems for the treatment of arthritic injuries: From classical treatment to nanomedicines

H Shang, A Younas, N Zhang - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Arthritic injuries happen frequently during a lifetime due to accidents, sports, aging,
diseases, etc. Such injuries can be cartilage/bone injuries, tendon injuries, ligament injuries …

Development of an intelligent, stimuli-responsive transdermal system for efficient delivery of Ibuprofen against rheumatoid arthritis

D Khan, M Qindeel, N Ahmed, MI Asad… - International Journal of …, 2021 - Elsevier
The present study aimed to fabricate and evaluate the therapeutic efficacy of pH-responsive
Ibuprofen (IB) nanoparticles (NPs) loaded transdermal hydrogel against rheumatoid arthritis …