Myeloid cells during viral infections and inflammation

AA Stegelmeier, JP van Vloten, RC Mould, EM Klafuric… - Viruses, 2019 - mdpi.com
Myeloid cells represent a diverse range of innate leukocytes that are crucial for mounting
successful immune responses against viruses. These cells are responsible for detecting …

HTLV-1 bZIP factor: the key viral gene for pathogenesis

M Matsuoka, JM Mesnard - Retrovirology, 2020 - Springer
Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL)
and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in …

Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade

DA Rauch, KC Conlon, M Janakiram… - Blood, The Journal …, 2019 - ashpublications.org
Immune checkpoint inhibitors are a powerful new tool in the treatment of cancer, with
prolonged responses in multiple diseases, including hematologic malignancies, such as …

HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

The tyrosine kinase KDR is essential for the survival of HTLV-1-infected T cells by stabilizing the Tax oncoprotein

S Mohanty, S Suklabaidya, A Lavorgna, T Ueno… - Nature …, 2024 - nature.com
The tyrosine kinase KDR is essential for the survival of HTLV-1-infected T cells by stabilizing the
Tax oncoprotein | Nature Communications Skip to main content Thank you for visiting …

CCR4 as a therapeutic target for cancer immunotherapy

O Yoshie - Cancers, 2021 - mdpi.com
Simple Summary CCR4 is a chemokine receptor selectively expressed on normal T cell
subsets such as type 2 helper T cells, skin-homing T cells and regulatory T cells, and on skin …

Identification and characterization of a novel enhancer in the HTLV-1 proviral genome

M Matsuo, T Ueno, K Monde, K Sugata… - Nature …, 2022 - nature.com
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus with constantly active
antisense transcription from the proviral genome. Here, Matsuo et al. perform proviral DNA …

Cytokine networks dysregulation during HTLV-1 infection and associated diseases

N Futsch, G Prates, R Mahieux, J Casseb, H Dutartre - Viruses, 2018 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a neural chronic
inflammation, called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

NF‐κB signaling mechanisms in HTLV‐1‐induced adult T‐cell leukemia/lymphoma

EW Harhaj, CZ Giam - The FEBS journal, 2018 - Wiley Online Library
The human T‐cell leukemia virus type 1 (HTLV‐1) is a complex deltaretrovirus linked to
adult T‐cell leukemia/lymphoma (ATLL), a fatal CD 4+ malignancy in 3–5% of infected …

Human T-cell lymphotropic virus type-1: a lifelong persistent infection, yet never truly silent

A Hirons, G Khoury, DFJ Purcell - The Lancet Infectious Diseases, 2021 - thelancet.com
Human T-cell lymphotropic virus type-1 (HTLV-1) has a large global burden and in some key
communities, such as Indigenous Australians living in remote areas, greater than 45% of …