Advances and opportunities in malaria population genomics

DE Neafsey, AR Taylor, BL MacInnis - Nature Reviews Genetics, 2021 - nature.com
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

Systems biology of malaria explored with nonhuman primates

MR Galinski - Malaria journal, 2022 - Springer
Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …

Population genomics: advancing understanding of nature

G Luikart, M Kardos, BK Hand, OP Rajora… - Population genomics …, 2019 - Springer
Population genomics is advancing our understanding of evolution, ecology, conservation,
agriculture, forestry, and human health by allowing new and long-standing questions to be …

Multi-omics approaches to improve malaria therapy

M Zhou, A Varol, T Efferth - Pharmacological Research, 2021 - Elsevier
Malaria contributes to the most widespread infectious diseases worldwide. Even though
current drugs are commercially available, the ever-increasing drug resistance problem by …

The spectrum of clinical biomarkers in severe malaria and new avenues for exploration

LPK Foko, G Narang, S Tamang, J Hawadak, J Jakhan… - Virulence, 2022 - Taylor & Francis
Globally, malaria is a public health concern, with severe malaria (SM) contributing a major
share of the disease burden in malaria endemic countries. In this context, identification and …

Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature

C Farias Amorim, F O. Novais, BT Nguyen… - PLoS neglected …, 2021 - journals.plos.org
Cutaneous leishmaniasis is a localized infection controlled by CD4+ T cells that produce IFN-
γ within lesions. Phagocytic cells recruited to lesions, such as monocytes, are then exposed …

MicroRNAs in the host-apicomplexan parasites interactions: a review of immunopathological aspects

CC Judice, C Bourgard, ACAV Kayano… - Frontiers in cellular …, 2016 - frontiersin.org
MicroRNAs (miRNAs), a class of small non-coding regulatory RNAs, have been detected in
a variety of organisms ranging from ancient unicellular eukaryotes to mammals. They have …

Applications of mycotoxin biomarkers in human biomonitoring for exposome-health studies: Past, present, and future

IO Owolabi, K Siwarak, B Greer, A Rajkovic… - Exposure and …, 2024 - Springer
This publication reviews the state-of-the-art human biological monitoring (HBM) of mycotoxin
biomarkers in breast milk, plasma, serum, and whole blood samples with a focus on the past …

[HTML][HTML] Diagnosis of cerebral malaria: Tools to reduce Plasmodium falciparum associated mortality

P Muppidi, E Wright, SC Wassmer… - Frontiers in cellular and …, 2023 - frontiersin.org
Cerebral malaria (CM) is a major cause of mortality in Plasmodium falciparum (Pf) infection
and is associated with the sequestration of parasitised erythrocytes in the microvasculature …

Transcript host-RNA signatures to discriminate bacterial and viral infections in febrile children

D Buonsenso, G Sodero, P Valentini - Pediatric Research, 2022 - nature.com
Traditional laboratory markers, such as white blood cell count, C-reactive protein, and
procalcitonin, failed to discriminate viral and bacterial infections in children. The lack of an …