[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Cellulose nanocrystals: Fundamentals and biomedical applications

P Mali, AP Sherje - Carbohydrate Polymers, 2022 - Elsevier
The present review explores the recent developments of cellulose nanocrystals, a class of
captivating nanomaterials in variety of applications. CNCs are made by acid hydrolysing …

[HTML][HTML] Research progress of in-situ gelling ophthalmic drug delivery system

Y Wu, Y Liu, X Li, D Kebebe, B Zhang, J Ren… - Asian journal of …, 2019 - Elsevier
Blindness and vision impairment are the most devastating global health problems resulting
in a substantial economic and social burden. Delivery of drug to particular parts of the …

Ocular drug delivery: Role of degradable polymeric nanocarriers for ophthalmic application

CH Tsai, PY Wang, IC Lin, H Huang, GS Liu… - International journal of …, 2018 - mdpi.com
Ocular drug delivery has been a major challenge for clinical pharmacologists and
biomaterial scientists due to intricate and unique anatomical and physiological barriers in …

Developments in Emerging Topical Drug Delivery Systems for Ocular Disorders

S Mandal, P Vishvakarma… - Current Drug Research …, 2024 - benthamdirect.com
According to the current information, using nano gels in the eyes have therapeutic benefits.
Industry growth in the pharmaceutical and healthcare sectors has been filled by …

Nanomaterial-based ophthalmic drug delivery

G Xie, S Lin, F Wu, J Liu - Advanced drug delivery reviews, 2023 - Elsevier
The low bioavailability and side effects of conventional drugs for eye disease necessitate the
development of efficient drug delivery systems. Accompanying the developments of …

[HTML][HTML] Intravitreal hydrogels for sustained release of therapeutic proteins

BC Ilochonwu, A Urtti, WE Hennink… - Journal of Controlled …, 2020 - Elsevier
This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery

JA Finbloom, F Sousa, MM Stevens… - Advanced drug delivery …, 2020 - Elsevier
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …

Recent advances of nanocellulose in drug delivery systems

N Hasan, L Rahman, SH Kim, J Cao, A Arjuna… - Journal of …, 2020 - Springer
Background Nanocellulose, which possesses great physical, chemical, and biological
properties, is a natural polymer derived from widely available native cellulose. It has …

[HTML][HTML] Current research trends of nanomedicines

Q Liu, J Zou, Z Chen, W He, W Wu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …