[HTML][HTML] Hypoxia as a critical player in extracellular vesicles-mediated intercellular communication between tumor cells and their surrounding microenvironment
H Branco, CPR Xavier, C Riganti… - Biochimica et Biophysica …, 2024 - Elsevier
In the past years, increasing attention has been paid to the role of extracellular vesicles
(EVs) as mediators of intercellular communication in cancer. These small size particles …
(EVs) as mediators of intercellular communication in cancer. These small size particles …
Hypoxia inducible factor-1ɑ as a potential therapeutic target for osteosarcoma metastasis
J Zhou, F Lan, M Liu, F Wang, X Ning… - Frontiers in …, 2024 - frontiersin.org
Osteosarcoma (OS) is a malignant tumor originating from mesenchymal tissue. Pulmonary
metastasis is usually present upon initial diagnosis, and metastasis is the primary factor …
metastasis is usually present upon initial diagnosis, and metastasis is the primary factor …
[HTML][HTML] Dual-functional 3D-printed porous bioactive scaffold enhanced bone repair by promoting osteogenesis and angiogenesis
S Li, Y Cui, H Liu, Y Tian, Y Fan, G Wang, J Wang… - Materials Today Bio, 2024 - Elsevier
The treatment of bone defects is a difficult problem in orthopedics. The excessive destruction
of local bone tissue at defect sites destroys blood supply and renders bone regeneration …
of local bone tissue at defect sites destroys blood supply and renders bone regeneration …
[HTML][HTML] Hydroxysafflor yellow A induced ferroptosis of Osteosarcoma cancer cells by HIF-1α/HK2 and SLC7A11 pathway
Y Zhu, L Yang, Y Yu, Y Xiong, P Xiao, X Fu… - Oncology …, 2024 - ncbi.nlm.nih.gov
Osteosarcoma is a very serious primary bone cancer with a high death rate and a dismal
prognosis. Since there is no permanent therapy for this condition, it is necessary to develop …
prognosis. Since there is no permanent therapy for this condition, it is necessary to develop …