Several studies has been reported on1, 3, 4-thiadiazole and their derivatives because of
their wide range of therapeutic activities. Many drugs containing thiadiazole derivatives are …

New drug development has been a convoluted, costly, tedious, and difficult job. Overall,
enormous sums of money are required for a new drug development pipeline through …

The derivatives 5, 7-dimethyl [1, 3, 4] thiadiazolo [3, 2-a] pyrimidin-4-ium-2-thiolate (1) and 7-
methyl-5-phenyl [1, 3, 4] thiadiazolo [3, 2-a] pyrimidin-4-ium-2-thiolate (2) were fully …

In the present study, the cytotoxic effects of a 1, 3-thiazolium-5-thiolate derivative of a
mesoionic compound, MIH 2.4 Bl, were assessed in the MCF-7 breast cancer cell line. The …

In this work, we report the synthesis of a new 1, 3-thiazolium-5-thiolate derivative of a
mesoionic compound (MIH 2.4 Bl) and the characterization of its selective cytotoxicity on a …

The principle of using amplification reactions of iodine was employed in this paper to
estimate the thiadiazole derivatives on basis of their reactions with iodine I chloroform …

Objective: To find out novel inhibitors for histamine 4 receptor (H4R), the target for various
allergic and inflammatory pathophysiological conditions. Methods: Homology modeling of …

In the recent times, many people around the world are suffering drug resistant in most of the
antibiotics used in different circumferences. In order to overcome the antibiotic resistance …