Cholinergic dysfunction in COVID-19: frantic search and hoping for the best

EH Nadwa, HM Al-Kuraishy, AI Al-Gareeb… - Naunyn-Schmiedeberg's …, 2023 - Springer
A novel coronavirus known as severe acute respiratory syndrome coronavirus type 2 (SARS-
CoV-2) is a potential cause of acute respiratory infection called coronavirus disease 2019 …

Use of Tox21 screening data to evaluate the COVID-19 drug candidates for their potential toxic effects and related pathways

S Sakamuru, R Huang, M Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Currently, various potential therapeutic agents for coronavirus disease-2019 (COVID-19), a
global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS …

Toxin-like peptides from the bacterial cultures derived from gut microbiome infected by SARS-CoV-2—new data for a possible role in the long COVID pattern

C Brogna, S Cristoni, B Brogna, DR Bisaccia, G Marino… - Biomedicines, 2022 - mdpi.com
It has been 3 years since the beginning of the SARS-CoV-2 outbreak, however it is as yet
little known how to care for the acute COVID-19 and long COVID patients. COVID-19 clinical …

A retrospective cohort study on early antibiotic use in vaccinated and unvaccinated COVID‐19 patients

C Brogna, L Montano, ME Zanolin… - Journal of Medical …, 2024 - Wiley Online Library
The bacteriophage behavior of SARS‐CoV‐2 during the acute and post‐COVID‐19 phases
appears to be an important factor in the development of the disease. The early use of …

[HTML][HTML] Toxin-like peptides in plasma, urine and faecal samples from COVID-19 patients

C Brogna, S Cristoni, M Petrillo, M Querci… - …, 2021 - ncbi.nlm.nih.gov
Background: SARS-CoV-2 that causes COVID-19 disease and led to the pandemic currently
affecting the world has been broadly investigated. Different studies have been performed to …

Temporal change in Syndecan-1 as a therapeutic target and a biomarker for the severity classification of COVID-19

F Ogawa, Y Oi, K Nakajima, R Matsumura… - Thrombosis journal, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) pneumonitis associated with
severe respiratory failure is associated with high mortality. The pathogenesis of COVID-19 is …

Long-chain acylcholines link butyrylcholinesterase to regulation of non-neuronal cholinergic signaling

JM Kinchen, RP Mohney… - Journal of proteome …, 2021 - ACS Publications
Acylcholines are comprised of an acyl chain esterified to a choline moiety; acetylcholine is
the best-characterized member of this class, functioning as a neurotransmitter in the central …

Microfabricated potentiometric sensor for personalized methacholine challenge tests during the COVID-19 pandemic

NB ElDin, MK Abd El-Rahman, HE Zaazaa… - Biosensors and …, 2021 - Elsevier
The methacholine challenge test is considered to be the gold standard bronchoprovocation
test used to diagnose asthma, and this test is always performed in pulmonary function labs …

Clinical characteristics and high risk factors of patients with Omicron variant strain infection in Hebei, China

L Wang, T Liu, H Yue, J Zhang, Q Sheng… - Frontiers in Cellular …, 2023 - frontiersin.org
Objective The Omicron variant has a weaker pathogenicity compared to the Delta variant but
is highly transmissible and elderly critically ill patients account for the majority. This study …

Severity predictors of COVID-19 in SARS-CoV-2 variant, delta and omicron period; single center study

F Ogawa, Y Oi, H Honzawa, N Misawa, T Takeda… - Plos one, 2022 - journals.plos.org
Background The outcomes of coronavirus disease 2019 (COVID-19) treatment have
improved due to vaccination and the establishment of better treatment regimens. However …