Review of flow cytometry as a tool for cell and gene therapy

CA Lazarski, PJ Hanley - Cytotherapy, 2024 - Elsevier
Quality control testing and analytics are critical for the development and manufacture of cell
and gene therapies, and flow cytometry is a key quality control and analytical assay that is …

Can transfusion-associated graft-versus-host disease (TA-GvHD) be prevented with leukoreduction alone?

JV Rodriguez, CA Tormey - Transfusion and Apheresis Science, 2022 - Elsevier
Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare but devastating
disease with a very high mortality rate. Because of the high mortality and lack of effective …

Development of new donor-specific and human leukocyte antigen antibodies after transfusion in adult lung transplantation

A Stoker, A Hicks, MC Wright, A Ali, J Klapper… - … of Cardiothoracic and …, 2023 - Elsevier
Objectives The development of new human leukocyte antigens (HLAs) and donor-specific
antibodies (DSAs) in patients are associated with worse outcomes following lung …

[HTML][HTML] Viable lymphocytes in fresh frozen plasma as a potential source of graft-versus-host disease: risks and solutions

B Brando - Blood Transfusion, 2021 - ncbi.nlm.nih.gov
The contamination of fresh frozen plasma (FFP) by residual leukocytes, red cells and
platelets is a well-known occurrence that must be taken into account during the manufacture …

[PDF][PDF] Hematological malignancies post-transplant-what's new?

J Trbojevic-Stankovic - era-online.org
Acute rejection and infection were the most common side effects in the early days of
transplantation. Nowadays, cardiovascular issues and malignancies are the major …