Diffuse large B-cell lymphoma: R-CHOP failure—what to do?

B Coiffier, C Sarkozy - Hematology 2014, the American Society …, 2016 - ashpublications.org
Although rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-
CHOP) is the standard treatment for patients with diffuse large B-cell lymphoma (DLBCL),∼ …

Emerging epigenetic-modulating therapies in lymphoma

D Sermer, L Pasqualucci, HG Wendel… - Nature reviews Clinical …, 2019 - nature.com
Despite considerable advances in the treatment of lymphoma, the prognosis of patients with
relapsed and/or refractory disease continues to be poor; thus, a continued need exists for …

MicroRNAs and epigenetics

C Moutinho, M Esteller - Advances in cancer research, 2017 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression mainly at
the posttranscriptional level. Similar to protein-coding genes, their expression is also …

Genetic and epigenetic alterations of micro RNA s and implications for human cancers and other diseases

M Tuna, AS Machado, GA Calin - Genes, Chromosomes and …, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are a well‐studied group of noncoding RNAs that control gene
expression by interacting mainly with messenger RNA. It is known that miRNAs and their …

miRNome expression analysis in canine diffuse large B-cell lymphoma

NO Elshafie, M Gribskov, NI Lichti… - Frontiers in …, 2023 - frontiersin.org
Introduction Lymphoma is a common canine cancer with translational relevance to human
disease. Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype, contributing …

Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

LS Kristensen, JW Hansen, SS Kristensen… - Clinical …, 2016 - Springer
Background The prognostic value of aberrant DNA methylation of cell-free circulating DNA
in plasma has not previously been evaluated in diffuse large B cell lymphoma (DLBCL). The …

MicroRNA profiling in canine multicentric lymphoma

KKL Craig, GA Wood, SM Keller, AJ Mutsaers… - PLoS …, 2019 - journals.plos.org
Lymphoma is the most common hematopoietic tumour in dogs and is remarkably similar to
the human disease. Tumour biomarker discovery is providing new tools for diagnostics and …

[HTML][HTML] Diagnostic and predictive biomarkers for lymphoma diagnosis and treatment in the era of precision medicine

R Sun, LJ Medeiros, KH Young - Modern Pathology, 2016 - Elsevier
Lymphomas are a group of hematological malignancies derived from lymphocytes.
Lymphomas are clinically and biologically heterogeneous and have overlapping diagnostic …

Benzene-induced aberrant miRNA expression profile in hematopoietic progenitor cells in C57BL/6 mice

H Wei, J Zhang, K Tan, R Sun, L Yin, Y Pu - International journal of …, 2015 - mdpi.com
Benzene is a common environmental pollutant that causes hematological alterations.
MicroRNAs (miRNAs) may play a role in benzene-induced hematotoxicity. In this study …

[HTML][HTML] Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma

LS Kristensen, F Asmar, K Dimopoulos, MK Nygaard… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's
lymphoma. Improvements in overall survival have been observed with the introduction of …