Bacterial survivors: Evaluating the mechanisms of antibiotic persistence
X Shi, A Zarkan - Microbiology, 2022 - microbiologyresearch.org
Bacteria withstand antibiotic onslaughts by employing a variety of strategies, one of which is
persistence. Persistence occurs in a bacterial population where a subpopulation of cells …
persistence. Persistence occurs in a bacterial population where a subpopulation of cells …
Mycobacterium tuberculosis strain with deletions in menT3 and menT4 is attenuated and confers protection in mice and guinea pigs
The genome of Mycobacterium tuberculosis encodes for a large repertoire of toxin-antitoxin
systems. In the present study, MenT3 and MenT4 toxins belonging to MenAT subfamily of TA …
systems. In the present study, MenT3 and MenT4 toxins belonging to MenAT subfamily of TA …
Neutralizing efficacy of encapsulin nanoparticles against SARS-CoV2 variants of concern
Rapid emergence of the SARS-CoV-2 variants has dampened the protective efficacy of
existing authorized vaccines. Nanoparticle platforms offer a means to improve vaccine …
existing authorized vaccines. Nanoparticle platforms offer a means to improve vaccine …
Understanding the reciprocal interplay between antibiotics and host immune system: how can we improve the anti-mycobacterial activity of current drugs to better …
HE Park, W Lee, MK Shin, SJ Shin - Frontiers in Immunology, 2021 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, remains a global
health threat despite recent advances and insights into host-pathogen interactions and the …
health threat despite recent advances and insights into host-pathogen interactions and the …
Functional and biochemical characterization of the MazEF6 toxin-antitoxin system of Mycobacterium tuberculosis
The Mycobacterium tuberculosis genome harbors nine toxin-antitoxin (TA) systems that are
members of the mazEF family, unlike other prokaryotes, which have only one or two …
members of the mazEF family, unlike other prokaryotes, which have only one or two …
Genome-wide analysis of the common bean (Phaseolus vulgaris) laccase gene family and its functions in response to abiotic stress
T Cheng, C Ren, J Xu, H Wang, B Wen, Q Zhao… - BMC Plant …, 2024 - Springer
Background Laccase (LAC) gene family plays a pivotal role in plant lignin biosynthesis and
adaptation to various stresses. Limited research has been conducted on laccase genes in …
adaptation to various stresses. Limited research has been conducted on laccase genes in …
Deciphering the role of VapBC13 and VapBC26 toxin antitoxin systems in the pathophysiology of Mycobacterium tuberculosis
The expansion of VapBC TA systems in M. tuberculosis has been linked with its fitness and
survival upon exposure to stress conditions. Here, we have functionally characterized …
survival upon exposure to stress conditions. Here, we have functionally characterized …
Rapid identification of secondary structure and binding site residues in an intrinsically disordered protein segment
S Chandra, G Chattopadhyay, R Varadarajan - Frontiers in Genetics, 2021 - frontiersin.org
Mycobacterium tuberculosis harbours nine toxin-antitoxin (TA) systems of the MazEF family.
MazEF TA modules are of immense importance due to the perceived role of the MazF toxin …
MazEF TA modules are of immense importance due to the perceived role of the MazF toxin …
Analysis of whiB7 in Mycobacterium tuberculosis reveals novel AT-hook deletion mutations
OF Davies-Bolorunduro, B Jaemsai, W Ruangchai… - Scientific Reports, 2023 - nature.com
Mutations in whiB7 have been associated with both hypersusceptibility and resistance to
various antibiotics in Mycobacterium tuberculosis (Mtb). Unlocking the secrets of antibiotic …
various antibiotics in Mycobacterium tuberculosis (Mtb). Unlocking the secrets of antibiotic …
HigB1 Toxin in Mycobacterium tuberculosis Is Upregulated During Stress and Required to Establish Infection in Guinea Pigs
The extraordinary expansion of Toxin Antitoxin (TA) modules in the genome of
Mycobacterium tuberculosis has received significant attention over the last few decades …
Mycobacterium tuberculosis has received significant attention over the last few decades …