Cancers are highly complex diseases that are characterized by not only the overgrowth of
malignant cells but also an altered immune response. The inhibition and reprogramming of …

Ovarian cancer response to immunotherapy is limited; however, the evaluation of
sensitive/resistant target treatment subpopulations based on stratification by tumor …

Tumor progression and the efficacy of immunotherapy are strongly influenced by the
composition and abundance of immune cells in the tumor microenvironment. Due to the …

Melanoma is the deadliest form of skin cancer. In the early stages, melanoma can be treated
successfully with surgery alone and survival rates are high, but after metastasis survival …

Recent breakthroughs in tumor immunotherapy such as immune checkpoint blockade (ICB)
antibodies, have demonstrated the capacity of the immune system to fight cancer in a …

Comprehensive multiplatform analysis of 80 uveal melanomas (UM) identifies four
molecularly distinct, clinically relevant subtypes: two associated with poor-prognosis …

ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) have recently entered into the
therapeutic scenario of metastatic breast cancer. However, only a proportion of patients …

Tumor-infiltrating lymphocytes (TILs) are associated with prognosis in various tumors.
However, it remains controversial whether the presence of TILs is related to an improved …

Esophageal cancer (EC) seriously threatens human health, and a promising new avenue for
EC treatment involves cancer immunotherapy. To improve the efficacy of EC immunotherapy …

In a relatively short period of time, treatment strategies for metastatic melanoma have
radically changed leading to an unprecedented improvement in patient survival. In this …