Recombinant expressing angiopep-2 fused anti-VEGF single chain Fab (scFab) could cross blood–brain barrier and target glioma
X Ji, H Wang, Y Chen, J Zhou, Y Liu - AMB Express, 2019 - Springer
In 2009, the FDA approved bevacizumab for the treatment of adult patients diagnosed with
recurrent glioblastoma. However, the poor permeability of the macromolecules across the …
recurrent glioblastoma. However, the poor permeability of the macromolecules across the …