Engineered nanomaterials for synergistic photo-immunotherapy

R Guo, S Wang, L Zhao, Q Zong, T Li, G Ling, P Zhang - Biomaterials, 2022 - Elsevier
Nanomaterial-synergized photodynamic therapy (PDT) and photothermal therapy (PTT), as
efficient and non-invasive treatment modalities, have shown significant advantages in …

Metal-organic frameworks applications in synergistic cancer photo-immunotherapy

PD Fernandes, FD Magalhães, RF Pereira, AM Pinto - Polymers, 2023 - mdpi.com
Conventional cancer therapies, such as radiotherapy and chemotherapy, can have long-
term side effects. Phototherapy has significant potential as a non-invasive alternative …

Anlotinib Induces a T Cell–Inflamed Tumor Microenvironment by Facilitating Vessel Normalization and Enhances the Efficacy of PD-1 Checkpoint Blockade in …

Y Su, B Luo, Y Lu, D Wang, J Yan, J Zheng, J Xiao… - Clinical Cancer …, 2022 - AACR
Purpose: Anlotinib has achieved good results in clinical trials of a variety of cancers.
However, the effects of anlotinib on the tumor microenvironment (TME) and systemic …

Image-guided in situ cancer vaccination with combination of multi-functional nano-adjuvant and an irreversible electroporation technique

JH Han, YY Lee, HE Shin, J Han, JM Kang, CPJ Wang… - Biomaterials, 2022 - Elsevier
Cancer immunotherapy is a next-generation treatment strategy; however, its side effects limit
its clinical translation. Here, a novel combination of a multi-functional nano-adjuvant (M-NA) …

Emerging trends in nano-driven immunotherapy for treatment of cancer

G Kandasamy, Y Karuppasamy, UM Krishnan - Vaccines, 2023 - mdpi.com
Despite advancements in the development of anticancer medications and therapies, cancer
still has the greatest fatality rate due to a dismal prognosis. Traditional cancer therapies …

Photothermal Prussian blue nanoparticles generate potent multi‐targeted tumor‐specific T cells as an adoptive cell therapy

EE Sweeney, P Sekhri, N Muniraj… - Bioengineering & …, 2024 - Wiley Online Library
Prussian blue nanoparticle‐based photothermal therapy (PBNP‐PTT) is an effective tumor
treatment capable of eliciting an antitumor immune response. Motivated by the ability of …

CD137 agonist potentiates the abscopal efficacy of nanoparticle-based photothermal therapy for melanoma

PB Balakrishnan, DK Ledezma, J Cano-Mejia… - Nano research, 2022 - Springer
Despite the promise of immunotherapy such as the immune checkpoint inhibitors (ICIs) anti-
PD-1 and anti-CTLA-4 for advanced melanoma, only 26%–52% of patients respond, and …

Anti-Fn14-conjugated Prussian blue nanoparticles as a targeted photothermal therapy agent for glioblastoma

NF Bonan, DK Ledezma, MA Tovar, PB Balakrishnan… - Nanomaterials, 2022 - mdpi.com
Prussian blue nanoparticles (PBNPs) are effective photothermal therapy (PTT) agents: they
absorb near-infrared radiation and reemit it as heat via phonon-phonon relaxations that, in …

[HTML][HTML] A mini-review of diagnostic and therapeutic nano-tools for pancreatitis

Q Zhang, S Li, Y Yu, Y Zhu, R Tong - International Journal of …, 2022 - ncbi.nlm.nih.gov
Pancreatitis is an inflammatory reaction of pancreatic tissue digestion, edema, bleeding and
even necrosis caused by activation of pancreatin due to various causes. In particular …

Nanotechnology-Based Diagnostic and Therapeutic Strategies for Neuroblastoma

H Yan, B Zhai, F Yang, Z Chen, Q Zhou… - Frontiers in …, 2022 - frontiersin.org
Neuroblastoma (NB), as the most common extracranial solid tumor in childhood, is one of
the critical culprits affecting children's health. Given the heterogeneity and invisibility of NB …