Wnt/β-catenin, a highly conserved signaling pathway, is involved in determining cell fate.
During heart development, Wnt signaling controls specification, proliferation and …

Insulin resistance and inflammation are strongly linked to non-alcoholic fatty liver disease
(NAFLD) as a feature of the metabolic syndrome. Furthermore, the role of dysregulation of …

Introduction REM sleep deprivation (SD) decreases tolerance of the rat heart to ischemia-
reperfusion (IR) injury; the underlying mechanisms, however, are unknown. This study …

Recently, the role of micro-ribonucleic acid-96 (miR-96) in alleviating neuropathic pain by
inhibiting the expression of NaV1. 3, an isoform of voltage-gated sodium channels, has been …

Objective (s): Trans-chalcone as the parent member of the chalcone series reduces
circulating levels of insulin and glucose. However, the cellular mechanism of these effects is …

Introduction Thyroid hormones are essential for proper development of many systems and
organs, including circulatory system. Thyroid deficiency during pregnancy may affect the …

Background Antenatal/early postnatal hypothyroidism weakens NO-mediated anticontractile
influence of endothelium in coronary arteries of adult rats, but it remains unclear whether this …

Objective. Trans-chalcone is a chalcone with hepatoprotective and anti-inflammatory effects.
However, the mechanism of these positive effects, especially on miR-451 as an …

Thyroid hormone deficiency during fetal life (fetal hypothyroidism) causes intrauterine
growth restriction (IUGR). Fetal hypothyroidism (FH) could attenuate normal cardiac …

Objective: The importance of swimming in bone metabolism during type 2 diabetes (T2DM)
is not well known. Receptor activator of nuclear factor-kB ligand (RANKL)/osteoprotegerin …