Apoptosis and autophagy: decoding calcium signals that mediate life or death
MW Harr, CW Distelhorst - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
Calcium is a versatile and dynamic 2nd messenger that is essential for the survival of all
higher organisms. In cells that undergo activation or excitation, calcium is released from the …
higher organisms. In cells that undergo activation or excitation, calcium is released from the …
Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid‐induced apoptosis
RV Sionov, R Spokoini, S Kfir‐Erenfeld… - Advances in cancer …, 2008 - Elsevier
Glucocorticoids (GCs) are commonly used in the treatment of hematopoietic malignancies
owing to their ability to induce apoptosis of these cancerous cells. Whereas some types of …
owing to their ability to induce apoptosis of these cancerous cells. Whereas some types of …
Genome-wide DNA methylation profiles changes associated with constant heat stress in pigs as measured by bisulfite sequencing
Y Hao, Y Cui, X Gu - Scientific Reports, 2016 - nature.com
Heat stress affects muscle development and meat quality in food animals; however, little is
known regarding its regulatory mechanisms at the epigenetic level, such as via DNA …
known regarding its regulatory mechanisms at the epigenetic level, such as via DNA …
Inositol 1,4,5-trisphosphate-induced Ca2+ signalling is involved in estradiol-induced breast cancer epithelial cell growth
C Szatkowski, JB Parys, H Ouadid-Ahidouch, F Matifat - Molecular cancer, 2010 - Springer
Background Ca 2+ is a ubiquitous messenger that has been shown to be responsible for
controlling numerous cellular processes including cell growth and cell death. Whereas the …
controlling numerous cellular processes including cell growth and cell death. Whereas the …
Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes
JK Molitoris, KS McColl, S Swerdlow… - Journal of Biological …, 2011 - ASBMB
Glucocorticoid hormones, including dexamethasone, induce apoptosis in lymphocytes and
consequently are used clinically as chemotherapeutic agents in many hematologic …
consequently are used clinically as chemotherapeutic agents in many hematologic …
Glucocorticoids downregulate Fyn and inhibit IP3-mediated calcium signaling to promote autophagy in T lymphocytes
MW Harr, KS McColl, F Zhong, JK Molitoris… - Autophagy, 2010 - Taylor & Francis
T cell receptor activation induces inositol 1, 4, 5 trisphosphate (IP3)-mediated calcium
signaling that is essential for cell metabolism and survival. Moreover, inhibitors of IP3 or …
signaling that is essential for cell metabolism and survival. Moreover, inhibitors of IP3 or …
Glucocorticoid-induced apoptosis and cellular mechanisms of myopathy
AJ Dirks-Naylor, CL Griffiths - The Journal of Steroid Biochemistry and …, 2009 - Elsevier
Glucocorticoid-induced myopathy is a common side effect of chronic glucocorticoid therapy.
Several mechanisms are currently being examined as ways in which glucocorticoid-induced …
Several mechanisms are currently being examined as ways in which glucocorticoid-induced …
Glucocorticoid-mediated inhibition of Lck modulates the pattern of T cell receptor-induced calcium signals by down-regulating inositol 1, 4, 5-trisphosphate receptors
MW Harr, Y Rong, MD Bootman, HL Roderick… - Journal of Biological …, 2009 - ASBMB
Glucocorticoids are potent immunosuppressive agents that block upstream signaling events
required for T cell receptor (TCR) activation. However, the mechanism by which …
required for T cell receptor (TCR) activation. However, the mechanism by which …
Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P3 in the cytoprotection of human fibroblasts by the glucocorticoid …
B Nieuwenhuis, A Lüth, J Chun, A Huwiler… - Journal of molecular …, 2009 - Springer
Glucocorticoids (GC) represent the most commonly used drugs for the treatment of acute
and chronic inflammatory skin diseases. However, the topical long-term therapy of GC is …
and chronic inflammatory skin diseases. However, the topical long-term therapy of GC is …
Genome-wide DNA methylation and gene expression profiles in cows subjected to different stress level as assessed by cortisol in milk
M Del Corvo, S Bongiorni, B Stefanon, S Sgorlon… - Genes, 2020 - mdpi.com
Dairy cattle health, wellbeing and productivity are deeply affected by stress. Its influence on
metabolism and immune response is well known, but the underlying epigenetic mechanisms …
metabolism and immune response is well known, but the underlying epigenetic mechanisms …