Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

If the last common ancestor of plants and animals was unicellular, comparison of the
developmental mechanisms of plants and animals would show that development was …

The transcription factors Batf3 and IRF8 are required for the development of CD8α+
conventional dendritic cells (cDCs), but the basis for their actions has remained unclear …

BACKGROUND: Allergic rhinitis represents a global health problem affecting 10% to 20% of
the population. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines have been …

Sequencing of exomes and genomes has revealed abundant genetic variation affecting the
coding sequences of human transcription factors (TFs), but the consequences of such …

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances
made during the last 10-15 years in fields such as developmental biology, molecular …

The nasal and bronchial mucosa present similarities and differences. Remodeling is defined
as “model again or differently, reconstruct” and is present in the airways of most if not all …

Arabidopsis (Arabidopsis thaliana) contains approximately 100 homeobox genes, many of
which have been shown to play critical roles in various developmental processes. Here we …

Bone is regulated by evolutionarily conserved signals that balance continuous differentiation
of bone matrix-producing cells against apoptosis and matrix removal. This is continued from …

Heterochronic genes control the timing of developmental programs. In C. elegans, two key
genes in the heterochronic pathway, lin‐4 and let‐7, encode small temporally expressed …