The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that regulate gene
expression post-transcriptionally by binding to messenger RNAs. miRNAs are important …

Mammary tumors are the second most common neoplasia in dogs. Due to the high similarity
of canine mammary tumors (CMT) to human breast cancers (HBC), human biomarkers of …

Simple Summary The high rate of cancers in both humans and in animals along with their
poor overall survival pose a major challenge in medicine. Therefore, a large amount of …

In recent years, many studies have focused their attention on the dog as a proper animal
model for human cancer. In dogs, mammary tumors develop spontaneously, involving a …

Background Breast (mammary) cancers in human (BC) and canine (CMT) patients share
clinical, pathological, and molecular similarities that suggest dogs may be a useful …

Mammary gland tumors (MGT) are the most common tumors in sexually intact female dogs.
The functional regulation of miRNAs, a type of noncoding RNAs (ncRNAs), in canine MGT …

Background Differentiating benign from canine malignant mammary tumors requires
invasive surgical biopsy. Circulating microRNAs (miRNA) may represent promising …

Abstract miR-206 and Bcl-2-associated athanogene 3 (BAG3) have been suggested as
important regulators in various cancer types. However, the biological role of miR-206 and …

Purpose Mammary gland tumors are the most common neoplastic diseases in elderly
female dogs, about 50% of which are considered to be malignant. Canine mammary tumors …