Cervical cancer immunotherapy: facts and hopes

L Ferrall, KY Lin, RBS Roden, CF Hung, TC Wu - Clinical Cancer Research, 2021 - AACR
It is a sad fact that despite being almost completely preventable through human
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …

Prophylactic and therapeutic HPV vaccines: current scenario and perspectives

Y Mo, J Ma, H Zhang, J Shen, J Chen… - Frontiers in cellular …, 2022 - frontiersin.org
Persistent human papillomavirus (HPV) infection is recognized as the main cause of cervical
cancer and other malignant cancers. Although early detection and treatment can be …

Immunologic treatments for precancerous lesions and uterine cervical cancer

P Vici, L Mariani, L Pizzuti, D Sergi, L Di Lauro… - Journal of Experimental …, 2014 - Springer
Abstract Development of HPV-associated cancers not only depends on efficient negative
regulation of cell cycle control that supports the accumulation of genetic damage, but also …

[PDF][PDF] Immunotherapy for human papillomavirus-associated disease and cervical cancer: review of clinical and translational research

SJ Lee, A Yang, TC Wu… - Journal of gynecologic …, 2016 - synapse.koreamed.org
Cervical cancer is the fourth most lethal women's cancer worldwide. Current treatments
against cervical cancer include surgery, radiotherapy, chemotherapy, and anti-angiogenic …

Current and future direction in treatment of HPV-related cervical disease

N Khairkhah, A Bolhassani, R Najafipour - Journal of Molecular Medicine, 2022 - Springer
Human papillomavirus (HPV) is the most common sexually transmitted virus in the world.
About 70% of cervical cancers are caused by the most oncogenic HPV genotypes of 16 and …

Antigen‐specific immunotherapy of cervical and ovarian cancer

CF Hung, TC Wu, A Monie, R Roden - Immunological reviews, 2008 - Wiley Online Library
We contrast the efforts to treat ovarian cancer and cervical cancer through vaccination
because of their different pathobiology. A plethora of approaches have been developed for …

Synergistic potential of immune checkpoint inhibitors and therapeutic cancer vaccines

M Oladejo, W Paulishak, L Wood - Seminars in Cancer Biology, 2023 - Elsevier
Cancer vaccines and immune checkpoint inhibitors (ICIs) function at different stages of the
cancer immune cycle due to their distinct mechanisms of action. Therapeutic cancer …

Current state in the development of candidate therapeutic HPV vaccines

A Yang, J Jeang, K Cheng, T Cheng… - Expert review of …, 2016 - Taylor & Francis
The identification of human papillomavirus (HPV) as an etiological factor for HPV-associated
malignancies creates the opportunity to control these cancers through vaccination …

Therapeutic human papillomavirus vaccines: current clinical trials and future directions

CF Hung, B Ma, A Monie, SW Tsen… - Expert opinion on …, 2008 - Taylor & Francis
Background: Cervical cancer is the second largest cause of cancer deaths in women
worldwide. It is now evident that persistent infection with high-risk human papillomavirus …

Current therapeutic vaccination and immunotherapy strategies for HPV-related diseases

JG Skeate, AW Woodham, MH Einstein… - Human vaccines & …, 2016 - Taylor & Francis
Carcinomas of the anogenital tract, in particular cervical cancer, remains one of the most
common cancers in women, and represent the most frequent gynecological malignancies …