High-grade glioma treatment response monitoring biomarkers: a position statement on the evidence supporting the use of advanced MRI techniques in the clinic, and …

OM Henriksen, M del Mar Álvarez-Torres… - Frontiers in …, 2022 - frontiersin.org
Objective Summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods …

Opportunities for improving brain cancer treatment outcomes through imaging-based mathematical modeling of the delivery of radiotherapy and immunotherapy

DA Hormuth II, M Farhat, C Christenson, B Curl… - Advanced drug delivery …, 2022 - Elsevier
Immunotherapy has become a fourth pillar in the treatment of brain tumors and, when
combined with radiation therapy, may improve patient outcomes and reduce the …

Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures

LS Hu, F D'Angelo, TM Weiskittel, FP Caruso… - Nature …, 2023 - nature.com
Sampling restrictions have hindered the comprehensive study of invasive non-enhancing
(NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present …

Assessment and prediction of glioblastoma therapy response: challenges and opportunities

D Qi, J Li, CC Quarles, E Fonkem, E Wu - Brain, 2023 - academic.oup.com
Glioblastoma is the most aggressive type of primary adult brain tumour. The median survival
of patients with glioblastoma remains approximately 15 months, and the 5-year survival rate …

Amine‐weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors

NS Cho, A Hagiwara, J Yao, DA Nathanson… - NMR in …, 2023 - Wiley Online Library
Amine‐weighted chemical exchange saturation transfer (CEST) magnetic resonance
imaging (MRI) is particularly valuable as an amine‐and pH‐sensitive imaging technique in …

A multi-reader comparison of normal-appearing white matter normalization techniques for perfusion and diffusion MRI in brain tumors

NS Cho, A Hagiwara, F Sanvito, BM Ellingson - Neuroradiology, 2023 - Springer
Purpose There remains no consensus normal-appearing white matter (NAWM)
normalization method to compute normalized relative cerebral blood volume (nrCBV) and …

Advanced MRI protocols to discriminate glioma from treatment effects: state of the art and future directions

DG Malik, TJ Rath, JC Urcuyo Acevedo… - Frontiers in …, 2022 - frontiersin.org
In the follow-up treatment of high-grade gliomas (HGGs), differentiating true tumor
progression from treatment-related effects, such as pseudoprogression and radiation …

Tumor treating fields increases blood-brain barrier permeability and relative cerebral blood volume in patients with glioblastoma

M Iv, L Naya, S Sanan, SL Van Buskirk… - The Neuroradiology …, 2024 - journals.sagepub.com
Background and objective 200 kHz tumor treating fields (TTFields) is clinically approved for
newly-diagnosed glioblastoma (nGBM). Because its effects on conventional surveillance …

Conventional and advanced imaging techniques in post-treatment glioma imaging

AY Li, M Iv - Frontiers in radiology, 2022 - frontiersin.org
Despite decades of advancement in the diagnosis and therapy of gliomas, the most
malignant primary brain tumors, the overall survival rate is still dismal, and their post …

Update on neuroimaging in brain tumours

M Smits - Current Opinion in Neurology, 2021 - journals.lww.com
Neuroimaging plays a central role but still often falls short on essential questions. Advanced
imaging acquisition and analysis techniques hold great promise for answering such …