Invited review: Opportunities for genetic improvement toward higher prolificacy in sheep

E Gootwine - Small Ruminant Research, 2020 - Elsevier
Breeding for higher prolificacy may improve lamb production efficiency in semi-intensive and
intensive sheep-production systems. Crossbreeding of native breeds with exotic prolific …

The Identification of Mutation in BMP15 Gene Associated with Litter Size in Xinjiang Cele Black Sheep

Z Niu, J Qin, Y Jiang, XD Ding, Y Ding, S Tang, H Shi - Animals, 2021 - mdpi.com
Simple Summary The gene for Bone Morphogenetic Protein 15 has multiple single-
nucleotide polymorphism sites related to fertility in sheep. To increase fertility, a better …

Genome-wide identification of a regulatory mutation in BMP15 controlling prolificacy in sheep

L Chantepie, L Bodin, J Sarry, F Woloszyn… - Frontiers in …, 2020 - frontiersin.org
The search for the genetic determinism of prolificacy variability in sheep has evidenced
several major mutations in genes playing a crucial role in the control of ovulation rate. In the …

Genome-wide scans identify known and novel regions associated with prolificacy and reproduction traits in a sub-Saharan African indigenous sheep (Ovis aries)

AT Dolebo, N Khayatzadeh, A Melesse, D Wragg… - Mammalian …, 2019 - Springer
Maximizing the number of offspring born per female is a key functionality trait in commercial-
and/or subsistence-oriented livestock enterprises. Although the number of offspring born is …

Effects of novel variants in BMP15 gene on litter size in Mongolia and Ujimqin sheep breeds

Y Wang, Z Chi, S Jia, S Zhao, G Cao, C Purev, M Cang… - Theriogenology, 2023 - Elsevier
Reproductive traits, such as ovulation rate and litter size, are important factors influencing
the sheep industry. The bone morphogenetic protein 15 (BMP15) is a major gene affecting …

Effects of New Mutations in BMPRIB, GDF9, BMP15, LEPR, and B4GALNT2 Genes on Litter Size in Sheep

X Ji, Z Cao, Q Hao, M He, M Cang, H Yu, Q Ma, X Li… - Veterinary …, 2023 - mdpi.com
Simple Summary BMPRIB, GDF9, BMP15, LEPR, and B4GALNT2 genes were regarded as
leading candidates for reproductive traits in sheep. Our recent studies identified 13 novel …

Investigation of G1 (c. 260G> A) polymorphism in exon 1 of GDF9 gene in Turkish sheepbreed Karayaka

K Kirikci, MA Cam, L Mercan - Turkish Journal of Veterinary & …, 2021 - journals.tubitak.gov.tr
GDF9 is an essential gene for normal follicular development and prolificacy in sheep. The
aim of this study was to determine the genetic polymorphism and G1 mutation of GDF9 gene …

Investigation of SNPs in BMP15 and GDF9 genes in" Çepni" and" Of" sheep in the Black Sea region of Turkey

K Kirikçi - Turkish Journal of Veterinary & Animal Sciences, 2023 - journals.tubitak.gov.tr
Sheep fertility genes have been studied in Turkey for many years. But so far it cannot be said
that a satisfactory result has been achieved in terms of the number of detected …

Identification of sequence variation in the oocyte-derived bone morphogenetic protein 15 (BMP15) gene (BMP15) associated with litter size in New Zealand sheep …

HA Najafabadi, M Khansefid, GG Mahmoud… - Molecular Biology …, 2021 - Springer
Advances in the study of reproductive traits indicate that functional variation in fertility genes
may be useful for improving sheep fertility. The aim of this study was to search for variation in …

An electrochemical protocol for CRISPR-mediated gene-editing of sheep embryonic fibroblast cells

S Eghbalsaied, WA Kues - Cells Tissues Organs, 2023 - karger.com
Genetic engineering of farm animals is commonly carried out via cell-mediated transfection
followed by somatic cell nuclear transfer. However, efficient transfer of exogenous DNA into …