Habitats are changing rapidly around the globe and urbanization is one of the primary
drivers. Urbanization changes food availability, environmental stressors, and the prevalence …

The genomic architecture underlying the origins and maintenance of biodiversity is an
increasingly accessible feature of species, due in large part to third‐generation sequencing …

Abstract Theory postulates that dietary specialization in mammalian herbivores is enabled
by a specialized set of liver enzymes that process the high concentrations of similar plant …

Herbivores rely heavily on liver enzymes to deal with plant secondary metabolites (PSMs)
due to their consumption on plant-based diets, but only a small amount of enzymes have …

Liver biotransformation enzymes have long been thought to enable animals to feed on diets
rich in xenobiotic compounds. However, despite decades of pharmacological research in …

Although herbivory is widespread among mammals, few species have adopted a strategy of
dietary specialization. Feeding on a single plant species often exposes herbivores to high …

Crystal structures of CYP2B35 and CYP2B37 from the desert woodrat were solved in
complex with 4-(4-chlorophenyl) imidazole (4-CPI). The closed conformation of CYP2B35 …

To be considered a dietary specialist, mammalian herbivores must consume large quantities
of a plant species considered “difficult” with respect to nutrient or toxin content, and possess …

The over two dozen CYP2B structures of human, rabbit, and woodrat enzymes solved in the
last decade have significantly enhanced our understanding of the structure-function …

This paper was designed to study stereoselective enrichment and changes in gene
expression when zebrafish (Danio rerio) embryo-larvae were exposed to racemic,(-)-or (+) …