A Raja, I Park, F Haq, SM Ahn - Cells, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer, with an increasing mortality rate. Aberrant expression of fibroblast growth factor 19–fibroblast growth …
CP Kovesdy, LD Quarles - American Journal of Physiology …, 2016 - journals.physiology.org
There is a strong association between elevated circulating fibroblast growth factor-23 (FGF23) levels and adverse outcomes in patients with chronic kidney disease (CKD) of all …
BC Lin, LR Desnoyers - Endocrine FGFs and Klothos, 2012 - Springer
Fibroblast growth factors (FGFs) and their cognate receptors, FGF receptors (FGFRs), play critical roles in a variety of normal developmental and physiological processes. Numerous …
A Rohrbeck, J Borlak - PloS one, 2009 - journals.plos.org
Background Lung cancer is a leading cause of cancer morbidity. To improve an understanding of molecular causes of disease a transgenic mouse model was investigated …
C Heinzle, A Gsur, M Hunjadi, Z Erdem, C Gauglhofer… - Cancer research, 2012 - AACR
A gly388arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in …
C Heinzle, Z Erdem, J Paur… - Current …, 2014 - ingentaconnect.com
Fibroblast growth factors (FGF) and their tyrosine kinase receptors (FGFR) support cell proliferation, survival and migration during embryonic development, organogenesis and …
L Lin, Q Wang, K Qian, Z Cao, J Xiao, X Wang… - Molecular …, 2018 - Springer
Blood-brain barrier (BBB) disruption is a common pathological feature of many neurological disorders including stroke and brain trauma, therefore is an important therapeutic target for …
E Frullanti, C Berking, N Harbeck… - European Journal of …, 2011 - journals.lww.com
Fibroblast growth factor receptor 4 (FGFR4) contains a Gly388Arg functional polymorphism (rs351855) that has shown contrasting results in association studies. In this study, we …
Á Quintanal-Villalonga, L Ojeda-Márquez, Á Marrugal… - Scientific reports, 2018 - nature.com
The FGFR4-388Arg variant has been related to poor prognosis in several types of cancer, including lung cancer. The mechanism underlying this association has not been addressed …