Bacteria surround their cell membrane with a net-like peptidoglycan layer, called sacculus,
to protect the cell from bursting and maintain its cell shape. Sacculus growth during …

Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and
protects them from osmotic lysis. The expansion and division of this structure therefore plays …

Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …

In vivo, bacterial actin MreB assembles into dynamic membrane-associated filamentous
structures that exhibit circumferential motion around the cell. Current knowledge of MreB …

One of the most common bacterial shapes is a rod, yet we have a limited understanding of
how this simple shape is constructed. While only six proteins are required for rod shape, we …

Fluorescence microscopy is the standard imaging technique to investigate the structures
and dynamics of living cells. However, increasing the spatial resolution comes at the cost of …

Most rod-shaped bacteria elongate by inserting new cell wall material into the inner surface
of the cell sidewall. This is performed by class A penicillin binding proteins (PBPs) and a …

Bacterial shape is physically determined by the peptidoglycan cell wall. The cell-wall-
synthesis machinery responsible for rod shape in Escherichia coli is the processive'Rod …

Metabolic turnover of mRNA is fundamental to the control of gene expression in all
organisms, notably in fast-adapting prokaryotes. In many bacteria, RNase Y initiates global …

Highlights•SEDS proteins work together with bPBPs to assemble the peptidoglycan
framework while aPBPs are required for repair and maturation.•Importance of FtsZ …