Cancer vaccines, which are designed to amplify tumour-specific T cell responses through
active immunization, have long been envisioned as a key tool of effective cancer …

Anti-angiogenesis therapy, a promising strategy against cancer progression, is limited by
drug-resistance, which could be attributed to changes within the tumor microenvironment …

Purpose Vitiligo-like depigmentation in patients with melanoma may be associated with
more favorable clinical outcome. We conducted a systematic review of patients with stage III …

Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …

Cytokines are molecular messengers that allow the cells of the immune system to
communicate with one another to generate a coordinated, robust, but self-limited response …

The incidence of colorectal cancer (CRC) is on the rise, and the prognosis for patients with
recurrent or metastatic disease is extremely poor. Although chemotherapy and radiation …

Cutaneous melanoma remains a management challenge. This year an estimated 55,000
Americans will receive a diagnosis of cutaneous melanoma, and 7900 will die from the …

The past decade has revealed that melanoma is comprised of multiple subclasses that can
be categorized on the basis of key features, including the clinical stage of disease, the …

The development of cancer is a multi-step process involving the gradual loss of regulation
over the growth and functional capabilities of normal cells. Much research has been focused …

Tumor vaccines have shown promise in early clinical trials. Among them, tumor cells
genetically engineered to secrete biologically active granulocyte-macrophage colony …