Hydrogel scaffolds for differentiation of adipose-derived stem cells

Q Huang, Y Zou, MC Arno, S Chen, T Wang… - Chemical Society …, 2017 - pubs.rsc.org
Natural extracellular matrices (ECMs) have been widely used as a support for the adhesion,
migration, differentiation, and proliferation of adipose-derived stem cells (ADSCs). However …

Emerging concepts in paracrine mechanisms in regenerative cardiovascular medicine and biology

CP Hodgkinson, A Bareja, JA Gomez… - Circulation research, 2016 - Am Heart Assoc
In the past decade, substantial evidence supports the paradigm that stem cells exert their
reparative and regenerative effects, in large part, through the release of biologically active …

Cell adhesion and long‐term survival of transplanted mesenchymal stem cells: A prerequisite for cell therapy

S Lee, E Choi, MJ Cha… - Oxidative medicine and …, 2015 - Wiley Online Library
The literature provides abundant evidence that mesenchymal stem cells (MSCs) are an
attractive resource for therapeutics and have beneficial effects in regenerating injured …

How to improve the survival of transplanted mesenchymal stem cell in ischemic heart?

L Li, X Chen, WE Wang, C Zeng - Stem Cells International, 2016 - Wiley Online Library
Mesenchymal stem cell (MSC) is an intensely studied stem cell type applied for cardiac
repair. For decades, the preclinical researches on animal model and clinical trials have …

Postischemic revascularization: from cellular and molecular mechanisms to clinical applications

JS Silvestre, DM Smadja, BI Levy - Physiological reviews, 2013 - journals.physiology.org
After the onset of ischemia, cardiac or skeletal muscle undergoes a continuum of molecular,
cellular, and extracellular responses that determine the function and the remodeling of the …

Hydrogel based approaches for cardiac tissue engineering

L Saludas, S Pascual-Gil, F Prósper, E Garbayo… - International journal of …, 2017 - Elsevier
Heart failure still represents the leading cause of death worldwide. Novel strategies using
stem cells and growth factors have been investigated for effective cardiac tissue …

Biomaterial-based scaffolds–current status and future directions

T Garg, AK Goyal - Expert opinion on drug delivery, 2014 - Taylor & Francis
Introduction: Biomaterial-based scaffold formulations (three-dimensional Porous matrix,
nano-fibre mesh, hydrogels and microspheres) are the major components that are used to …

Innovative strategies for intervertebral disc regenerative medicine: from cell therapies to multiscale delivery systems

N Henry, J Clouet, J Le Bideau, C Le Visage… - Biotechnology …, 2018 - Elsevier
As our understanding of the physiopathology of intervertebral disc (IVD) degeneration has
improved, novel therapeutic strategies have emerged, based on the local injection of cells …

Assessing glucose and oxygen diffusion in hydrogels for the rational design of 3D stem cell scaffolds in regenerative medicine

L Figueiredo, R Pace, C D'arros… - Journal of tissue …, 2018 - Wiley Online Library
Hydrogels are attractive biomaterials for replicating cellular microenvironments, but attention
needs to be given to hydrogels diffusion properties. A large body of literature shows the …

Chemical cross-linking methods for cell encapsulation in hydrogels

C Echalier, L Valot, J Martinez, A Mehdi… - Materials Today …, 2019 - Elsevier
Cell-encapsulating hydrogels are of tremendous interest in regenerative medicine. Tissue
engineering relies on biomaterials able to act as artificial extracellular matrices to guide cells …