For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …

Ebola viruses and Marburg viruses, members of the filovirus family, are zoonotic pathogens
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …

Four families of enveloped RNA viruses, filoviruses, flaviviruses, arenaviruses, and
bunyaviruses, cause hemorrhagic fevers. These viruses are maintained in specific natural …

Viruses manipulate the function of dendritic cells (DCs) to enhance their entry, spread,
survival and transmission. This review summarises recently published work identifying how …

Abstract Ebolaviruses and Marburgviruses (family Filoviridae) are among the most virulent
pathogens for humans and great apes causing severe haemorrhagic fever and death within …

Ebola and Marburg viruses are the only members of the Filoviridae family (order
Mononegavirales), a group of viruses characterized by a linear, non-segmented, single …

Disseminated intravascular coagulation (DIC) has been understood as a consumptive
coagulopathy. However, impaired hemostasis is a component of DIC that occurs in a …

The clinical syndrome referred to as viral hemorrhagic fever (VHF) can be caused by several
different families of RNA viruses, including select members of the arenaviruses …

Ebola causes highly lethal hemorrhagic fever in humans with no licensed countermeasures.
Its virulence can be attributed to several immunoevasion mechanisms: an early inhibition of …

Ebola virus is a single-stranded, negative-sense RNA virus that causes severe hemorrhagic
fever in humans and non-human primates. This virus is unreceptive to a large portion of the …