Cystic fibrosis is a hereditary disease that mainly affects secretory organs in humans. It is
caused by mutations in the gene encoding CFTR with the most common phenylalanine …

Cystic fibrosis (CF) is the most common genetic disorder that causes a significant damage in
secretory epithelial cells due to the defective ion flux across the cystic fibrosis …

Introduction Mitochondria dysfunction has been extensively implicated in the progression of
these metabolic disorders, their role in placental tissue of diabetic and/or obese pregnant …

Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease, caused by
mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator …

The specific role of the chloride anion (Cl−) as a signalling effector or second messenger
has been increasingly recognized in recent years. It could represent a key factor in the …

Innate immune cells, epithelial cells, and many other cell types are capable of detecting
infection or tissue injury, thus mounting regulated immune response. Inflammasomes are …

Introduction Oxidative stress may play an important role in the pathophysiology of cystic
fibrosis (CF). This review aimed to quantify CF-related redox imbalances. Methods …

A meta-analysis of 13 independent microarray data sets was performed and gene
expression profiles from cystic fibrosis (CF), similar disorders (COPD: chronic obstructive …

Background/Aims: Cystic Fibrosis (CF) is caused by mutations in the CFTR gene, encoding
a cAMP-activated chloride (Cl-) channel. We have previously demonstrated that the …

Pulmonary disease is the main cause of the morbidity and mortality of patients affected by
cystic fibrosis (CF). The lung pathology is dominated by excessive recruitment of neutrophils …