Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription
factor belonging, together with PPARγ and PPARβ/δ, to the NR1C nuclear receptor …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver dysfunction in
the Western world and is increasing owing to its close association with obesity and insulin …

Objective Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor
expressed in tissues with high oxidative activity that plays a central role in metabolism. In …

Peroxisome proliferator–activated receptors (PPARs) regulate energy metabolism and
hence are therapeutic targets in metabolic diseases such as type 2 diabetes and non …

Nonalcoholic fatty liver disease (NAFLD) and its progressive form nonalcoholic
steatohepatitis (NASH) comprise a spectrum of chronic liver diseases in the global …

Vitamin A is required for important physiological processes, including embryogenesis,
vision, cell proliferation and differentiation, immune regulation, and glucose and lipid …

Cardiometabolic disease is an increasing cause of morbidity and death in society. While M1-
like macrophages contribute to metabolic inflammation and insulin resistance, those …

Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) comprises a wide spectrum of liver
injuries from simple steatosis to steatohepatitis and cirrhosis. Non-Alcoholic Steatohepatitis …

Background: Increased consumption of folic acid is prevalent, leading to concerns about
negative consequences. The effects of folic acid on the liver, the primary organ for folate …

Emerging evidence suggests that impaired regulation of adipocyte lipolysis contributes to
the proinflammatory immune cell infiltration of metabolic tissues in obesity, a process that is …