Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Recent advances in regenerative biomaterials

D Cao, J Ding - Regenerative Biomaterials, 2022 - academic.oup.com
Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

Targeted modulation of immune cells and tissues using engineered biomaterials

P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

[HTML][HTML] Controlling timing and location in vaccines

DJ Irvine, A Aung, M Silva - Advanced Drug Delivery Reviews, 2020 - Elsevier
Vaccines are one of the most powerful technologies supporting public health. The adaptive
immune response induced by immunization arises following appropriate activation and …

[HTML][HTML] Polysaccharide-based nanomedicines for cancer immunotherapy: A review

Y Zeng, Y Xiang, R Sheng, H Tomás, J Rodrigues… - Bioactive Materials, 2021 - Elsevier
Cancer immunotherapy is an effective antitumor approach through activating immune
systems to eradicate tumors by immunotherapeutics. However, direct administration of …

Cryo-shocked cancer cells for targeted drug delivery and vaccination

T Ci, H Li, G Chen, Z Wang, J Wang, P Abdou, Y Tu… - Science …, 2020 - science.org
Live cells have been vastly engineered into drug delivery vehicles to leverage their targeting
capability and cargo release behavior. Here, we describe a simple method to obtain …

From design to clinic: engineered nanobiomaterials for immune normalization therapy of cancer

M Saeed, F Chen, J Ye, Y Shi, T Lammers… - Advanced …, 2021 - Wiley Online Library
The tumor immune microenvironment (TIME) is comprised of a complex milieu that
contributes to stunting antitumor immune responses by restricting T cells to accumulate in …

Hydroxyapatite nanoparticles for improved cancer theranostics

S Kargozar, S Mollazadeh, F Kermani… - Journal of Functional …, 2022 - mdpi.com
Beyond their well-known applications in bone tissue engineering, hydroxyapatite
nanoparticles (HAp NPs) have also been showing great promise for improved cancer …

Biomaterials as local niches for immunomodulation

K Adu-Berchie, DJ Mooney - Accounts of chemical research, 2020 - ACS Publications
Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …

Hematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow-targeted leukaemia drug delivery

J Li, H Wu, Z Yu, Q Wang, X Zeng, W Qian, S Lu… - Nature …, 2024 - nature.com
Leukemia is a kind of hematological malignancy originating from bone marrow, which
provides essential signals for initiation, progression, and recurrence of leukemia. However …