In most cancer treatments, chemotherapy is currently necessary; hence, more attention was devoted to developing new methods for designing drug delivery systems (DDS) with …
Nanoparticles (NPs) for targeted therapy are required to have appropriate size, stability, drug loading and release profiles, and efficient targeting ligands. However, many of the …
T Sadhukha, TD O'Brien, S Prabha - Journal of controlled Release, 2014 - Elsevier
Poor availability in deep-seated solid tumors is a significant challenge that limits the effectiveness of currently used anticancer drugs. Approaches that can specifically enhance …
LA Omtvedt, KA Kristiansen, WI Strand… - … Research Part A, 2021 - Wiley Online Library
Modification of drug delivery materials with beta‐cyclodextrins (β‐CyD) is known to increase solubility of poorly water‐soluble drugs, protect drugs from degradation and sustain release …
Lung cancer is often diagnosed at an advanced stage where tumors are usually inoperable and first-line therapies are inefficient and have off-targeted adverse effects, resulting in poor …
K De Clercq, F Xie, O De Wever, B Descamps… - Scientific Reports, 2019 - nature.com
Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) …
Paclitaxel-loaded poly (lactic acid-co-glycolic acid)(PLGA) microspheres containing different portions of human serum albumin microparticles (mHSA) were prepared via an in situ …
A Gonsalves, JU Menon - International Journal of Molecular Sciences, 2024 - mdpi.com
Nanoparticles (NPs) have shown significant potential for pulmonary administration of therapeutics for the treatment of chronic lung diseases in a localized and sustained manner …
In this study, poly (d, l-lactide-co-glycolide), PLGA, was developed as an in situ forming implants (ISFIs) to improve the therapeutic efficiency and to devoid the adverse effects of the …