Abstract 17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many
tissue and organ functions in physiology. The effects of E2 on cells are mediated by the …

Simple Summary Human health is significantly affected by microbial infections. One of the
largest determinants of the outcomes of such infections is the host immune response. Too …

Breast cancer is a heterogeneous disease manifesting diversity at the molecular,
histological and clinical level. The development of breast cancer classification was centered …

As early as the 1800s, the actions of estrogen have been implicated in the development and
progression of breast cancer. The estrogen receptor (ER) was identified in the late 1950s …

For many decades, androgens have dominated endocrine research in hair growth control.
Androgen metabolism and the androgen receptor currently are the key targets for systemic …

Melatonin is an indole hormone produced mainly by the pineal gland. We have previously
demonstrated that melatonin interferes with estrogen (E 2) signaling in MCF7 cells by …

Estrogen modifies human emotion and cognition and impacts symptoms of schizophrenia.
We hypothesized that the variation in the estrogen receptor alpha (ESR1) gene and cortical …

Alterations in the abundance or activities of alternative splicing regulators generate
alternatively spliced variants that contribute to multiple aspects of tumor establishment …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
memory loss and disordered cognition. Women have a higher AD incidence than men …

Clinical and experimental studies show that estrogens can have beneficial effects on
hippocampus-dependent cognitive functions that may be mediated by estrogen receptor …