The pineal eye of Xenopus laevis tadpoles is directly photosensitive. A sudden reduction in
light intensity produces a burst of activity in the pineal ganglion cells, which is closely …

Movement, the fundamental component of behavior and the principal extrinsic action of the
brain, is produced when skeletal muscles contract and relax in response to patterns of action …

The peak concentration and rate of clearance of neurotransmitter from the synaptic cleft are
important determinants of synaptic function, yet the neurotransmitter concentration time …

The ion current induced by the glutamate receptor agonist N-methyl-D-aspartate (NMDA) in
voltage-clamped hippocampal neurons was inhibited by ethanol (EtOH). Inhibition …

Excitatory neurotransmission mediated by NMDA (N-methyl-d-aspartate) receptors is
fundamental to the physiology of the mammalian central nervous system. These receptors …

1. We have developed a 19-compartment cable model of a guinea pig CA3 pyramidal
neuron. Each compartment is allowed to contain six active ionic conductances: gNa, gCa …

Individual rat hippocampal neurons, grown in isolation from other neurons on small spots of
permissive substrate, were studied in order to characterize the electrical properties of the …

SYNAPTIC release of glutamate results in a two component excitatory postsynaptic current
(epsc) at many vertebrate central synapses1–6. Non-N-methyl-D-aspartate receptors …

Dose-response curves for activation of excitatory amino acid receptors on mouse embryonic
hippocampal neurons in culture were recorded for 15 excitatory amino acids, including the L …

Communication between nerve cells in the central nervous system (CNS) occurs at
synapses, which are specialized sites between the presynaptic nerve terminal and the …