A blueprint for a multi-disease, multi-domain Bayesian adaptive platform trial incorporating adult and paediatric subgroups: the Staphylococcus aureus Network …

RK Mahar, A McGlothlin, M Dymock, TC Lee, RJ Lewis… - Trials, 2023 - Springer
Abstract The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is a
multifactorial Bayesian adaptive platform trial that aims to improve the way that S. aureus …

Analysis of Nonconcurrent Controls in Adaptive Platform Trials: Separating Randomized and Nonrandomized Information

IC Marschner, IM Schou - Biometrical Journal, 2024 - Wiley Online Library
Adaptive platform trials allow treatments to be added or dropped during the study, meaning
that the control arm may be active for longer than the experimental arms. This leads to …