The dynamics of GABA signaling: revelations from the circadian pacemaker in the suprachiasmatic nucleus

HE Albers, JC Walton, KL Gamble, JK McNeill IV… - Frontiers in …, 2017 - Elsevier
Virtually every neuron within the suprachiasmatic nucleus (SCN) communicates via
GABAergic signaling. The extracellular levels of GABA within the SCN are determined by a …

5-HT3 receptor antagonists in neurologic and neuropsychiatric disorders: the iceberg still lies beneath the surface

G Fakhfouri, R Rahimian, J Dyhrfjeld-Johnsen… - Pharmacological …, 2019 - Elsevier
HT 3 receptor antagonists, first introduced to the market in the mid-1980s, are proven
efficient agents to counteract chemotherapy-induced emesis. Nonetheless, recent …

Building a 5-HT3A receptor expression map in the mouse brain

Y Koyama, M Kondo, S Shimada - Scientific reports, 2017 - nature.com
Of the many serotonin receptors, the type 3 receptors (5-HT3R) are the only ionotropic ones,
playing a key role in fast synaptic transmission and cognitive and emotional brain function …

From behavioral context to receptors: serotonergic modulatory pathways in the IC

LM Hurley, MR Sullivan - Frontiers in neural circuits, 2012 - frontiersin.org
In addition to ascending, descending, and lateral auditory projections, inputs extrinsic to the
auditory system also influence neural processing in the inferior colliculus (IC). These types …

Changing the cortical conductor's tempo: neuromodulation of the claustrum

KLL Wong, A Nair, GJ Augustine - Frontiers in neural circuits, 2021 - frontiersin.org
The claustrum is a thin sheet of neurons that is densely connected to many cortical regions
and has been implicated in numerous high-order brain functions. Such brain functions arise …

The role of serotonin, vasopressin, and serotonin/vasopressin interactions in aggressive behavior

TR Morrison, RH Melloni - Neuroscience of Aggression, 2014 - Springer
Aggression control has been investigated across species and is centrally mediated within
various brain regions by several neural systems that interact at different levels. The debate …

A review of the effects of different types of social behaviors on the recruitment of neuropeptides and neurotransmitters in the nucleus accumbens

JM Borland - Frontiers in Neuroendocrinology, 2025 - Elsevier
There is a lack of understanding of the neural mechanisms regulating the rewarding effects
of social interactions. A significant contributor to this lack of clarity is the diversity of social …

Serotonin type-3 receptors differentially modulate anxiety and aggression during withdrawal from adolescent anabolic steroid exposure

TR Morrison, LA Ricci, AS Puckett, J Joyce… - Hormones and …, 2020 - Elsevier
Abstract Male Syrian hamsters (Mesocricetus auratus) administered anabolic/androgenic
steroids during adolescent development display increased aggression and decreased …

Repeated fluoxetine administration during adolescence stimulates aggressive behavior and alters serotonin and vasopressin neural development in hamsters.

LA Ricci, RH Melloni Jr - Behavioral neuroscience, 2012 - psycnet.apa.org
Fluoxetine is the only selective serotonin reuptake inhibitor registered for the treatment of
major depressive disorder in pediatric populations, despite reports that it is …

The interplay between 5-HT2C and 5-HT3A receptors in the dorsal periaqueductal gray mediates anxiety-like behavior in mice

LT Lopes, L Canto-de-Souza… - Behavioural Brain …, 2022 - Elsevier
The monoamine neurotransmitter serotonin (5-HT) modulates anxiety by its activity on 5-HT
2C receptors (5-HT 2C R) expressed in the dorsal periaqueductal gray (dPAG). Here, we …