Prediabetes is a state of elevated plasma glucose in which the threshold for diabetes has
not yet been reached and can predispose to the development of type 2 diabetes and …

Proper regulation and management of energy, substrate diversity and quantity, as well as
macromolecular synthesis and breakdown processes, are fundamental to cellular and …

Highly ordered interactions between immune and metabolic responses are evolutionarily
conserved and paramount for tissue and organismal health. Disruption of these interactions …

Mood disorders and type 2 diabetes mellitus (T2DM) are prevalent conditions that often co-
occur. We reviewed the available evidence from longitudinal and Mendelian randomisation …

Obesity is associated with a disturbed adipose tissue (AT) function characterized by
adipocyte hypertrophy, an impaired lipolysis and pro-inflammatory phenotype, which …

β-sitosterol (SIT), the most abundant bioactive component of vegetable oil and other plants,
is a highly potent antidiabetic drug. Our previous studies show that SIT controls …

Metabolic disorders, such as obesity, type 2 diabetes mellitus, and nonalcoholic fatty liver
disease, are characterized by chronic low-grade tissue and systemic inflammation. During …

Metformin, one of the oldest oral antidiabetic agents and still recommended by almost all
current guidelines as the first-line treatment for type 2 diabetes mellitus (T2DM), has become …

Abstract Background Both Alzheimer's disease (AD) and type 2 diabetes (T2D) share
common pathological features including inflammation, insulin signaling alterations, or …

Developing an oral nano-based delivery system for diabetes combines the desirable patient
compliance of oral delivery with the tunable physicochemical features of nano-systems …