The analysis of peptides and proteins as well as the grander scope of proteomics (large
scale study of proteins) has been advanced by the development of a versatile array of ion …

Mass spectrometric identification of all types of molecules relies on the observation and
interpretation of ion fragmentation patterns. Peptides, proteins, carbohydrates, and nucleic …

In recent years, electron capture (ECD) and electron transfer dissociation (ETD) have
emerged as two of the most useful methods in mass spectrometry‐based protein analysis …

Unraveling of all of the information contained in proteomes poses a tremendous chemical
challenge, which is balanced by the promise of potentially transformational knowledge …

Optical spectroscopy has contributed enormously to our knowledge of the structure and
dynamics of atoms and molecules and is now emerging as a cornerstone of the gas phase …

Tandem mass spectrometry involves isolation of specific precursor ions and their
subsequent excitation through collision‐, photon‐, or electron‐mediated activation …

DNA multiply charged anions stored in a quadrupole ion trap undergo one-photon electron
ejection (oxidation) when subjected to laser irradiation at 260 nm (4.77 eV). Electron …

This manuscript describes a new experimental setup that allows to perform tandem ion
mobility spectrometry (IMS) measurements and which is coupled to a high resolution time-of …

O-Glycopeptides are often acidic owing to the frequent occurrence of acidic saccharides in
the glycan, rendering traditional proteomic workflows that rely on positive mode tandem …

The field of proteomics almost uniformly relies on peptide cation analysis, leading to an
underrepresentation of acidic portions of proteomes, including relevant acidic …