Probiotics, prebiotics and synbiotics: Safe options for next-generation therapeutics

MK Yadav, I Kumari, B Singh, KK Sharma… - Applied microbiology and …, 2022 - Springer
Probiotics have been considered as an economical and safe alternative for the treatment of
a large number of chronic diseases and improvement of human health. They are known to …

Gut microbes from the phylogenetically diverse genus Eubacterium and their various contributions to gut health

A Mukherjee, C Lordan, RP Ross, PD Cotter - Gut microbes, 2020 - Taylor & Francis
Over the last two decades our understanding of the gut microbiota and its contribution to
health and disease has been transformed. Among a new 'generation'of potentially beneficial …

Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

X Zhu, Z Chen, W Shen, G Huang, JM Sedivy… - Signal transduction and …, 2021 - nature.com
Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

Targeting cancer-promoting inflammation—have anti-inflammatory therapies come of age?

J Hou, M Karin, B Sun - Nature reviews Clinical oncology, 2021 - nature.com
The immune system has crucial roles in cancer development and treatment. Whereas
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …

Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice

Z Zhang, X Tian, JY Lu, K Boit, J Ablaeva, FT Zakusilo… - Nature, 2023 - nature.com
Abundant high-molecular-mass hyaluronic acid (HMM-HA) contributes to cancer resistance
and possibly to the longevity of the longest-lived rodent—the naked mole-rat,. To study …

Microbiome and human aging: probiotic and prebiotic potentials in longevity, skin health and cellular senescence

JL Boyajian, M Ghebretatios, S Schaly, P Islam… - Nutrients, 2021 - mdpi.com
The role of the microbiome in human aging is important: the microbiome directly impacts
aging through the gastrointestinal system. However, the microbial impact on skin has yet to …

Demystifying the manipulation of host immunity, metabolism, and extraintestinal tumors by the gut microbiome

Z Zhang, H Tang, P Chen, H Xie, Y Tao - Signal transduction and …, 2019 - nature.com
The trillions of microorganisms in the gut microbiome have attracted much attention recently
owing to their sophisticated and widespread impacts on numerous aspects of host …

Gut microbiota influence tumor development and Alter interactions with the human immune system

Y Ge, X Wang, Y Guo, J Yan, A Abuduwaili… - Journal of Experimental …, 2021 - Springer
Recent scientific advances have greatly enhanced our understanding of the complex link
between the gut microbiome and cancer. Gut dysbiosis is an imbalance between …

Akkermansia muciniphila as a Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression: A Role Mediated by Gut–Liver …

H Jian, Y Liu, X Wang, X Dong, X Zou - International Journal of Molecular …, 2023 - mdpi.com
Appreciation of the importance of Akkermansia muciniphila is growing, and it is becoming
increasingly relevant to identify preventive and/or therapeutic solutions targeting gut–liver …

Dietary fibers from fruits and vegetables and their health benefits via modulation of gut microbiota

J Cui, Y Lian, C Zhao, H Du, Y Han… - … Reviews in Food …, 2019 - Wiley Online Library
Dietary fibers (DFs) regulate host health through various mechanisms related to their dietary
sources, specific physicochemical structures, fermentability, and physiological properties in …