Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Nonalcoholic fatty liver disease (NAFLD) is a main hepatic manifestation of metabolic
syndrome. It represents a wide spectrum of histopathological abnormalities ranging from …

Non-alcoholic fatty liver disease (NAFLD), currently the leading cause of global chronic liver
disease, has emerged as a major public health problem, more efficient therapeutics of which …

Non-alcoholic steatohepatitis (NASH) develops from non-alcoholic fatty liver disease
(NAFLD). Currently, around 25% of the population is estimated to have NAFLD, and 25% of …

The subcutaneous adipose tissue (SAT) is the largest and best storage site for excess lipids.
However, it has a limited ability to expand by recruiting and/or differentiating available …

Phagocytes are key cellular participants determining important aspects of host exposure to
nanomaterials, initiating clearance, biodistribution and the tenuous balance between host …

The liver is an essential metabolic organ, and its metabolic activity is tightly controlled by
insulin and other metabolic hormones. Glucose is metabolized into pyruvate through …

Background Insulin resistance (IR) is one of the major hallmark for pathogenesis and
etiology of type 2 diabetes mellitus (T2DM). IR is directly interlinked with various …

The extracellular matrix (ECM) is a network of different proteins and proteoglycans that
controls differentiation, migration, repair, survival, and development, and it seems that its …

Based on the assumption that characterizing the history of a disease will help in improving
practice while offering a clue to research, this article aims at reviewing the history of …