Network pharmacology prediction and molecular docking-based strategy to explore the potential mechanism of Huanglian Jiedu Decoction against sepsis

X Li, S Wei, S Niu, X Ma, H Li, M Jing, Y Zhao - Computers in biology and …, 2022 - Elsevier
Abstract Background Huanglian Jiedu Decoction (HLJDD) is a classical herbal formula with
potential efficacy in the treatment of sepsis. However, the main components and potential …

Phytochemical Composition of Different Botanical Parts of Morus Species, Health Benefits and Application in Food Industry

AR Memete, AV Timar, AN Vuscan, F Miere, AC Venter… - Plants, 2022 - mdpi.com
In recent years, mulberry has acquired a special importance due to its phytochemical
composition and its beneficial effects on human health, including antioxidant, anticancer …

[HTML][HTML] Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling

B Zhou, J Zhang, Y Chen, Y Liu, X Tang, P Xia… - Aging (albany …, 2022 - ncbi.nlm.nih.gov
Objective: Research suggests that Puerarin may protect against sepsis-induced myocardial
damage. However, the mechanisms responsible for Puerarin's cardioprotective effect remain …

Pharmacological Properties of Morus nigra L. (Black Mulberry) as A Promising Nutraceutical Resource

SH Lim, CI Choi - Nutrients, 2019 - mdpi.com
Mulberry plants belonging to the Moraceae family have been grown for the purpose of being
the nutrient source for silk worm and raw materials for the preparation of jams, marmalades …

Mulberry plant as a source of functional food with therapeutic and nutritional applications: A review

M Maqsood, R Anam Saeed, A Sahar… - Journal of food …, 2022 - Wiley Online Library
Medicinal plants from the family Moraceae have diverse applications in agriculture,
cosmetics, food, and the pharmaceutical industry. Their extensive spectrum of …

C-reactive protein-to-albumin ratio as a biomarker in patients with sepsis: a novel LASSO-COX based prognostic nomogram

X Zhou, S Fu, Y Wu, Z Guo, W Dian, H Sun, Y Liao - Scientific Reports, 2023 - nature.com
To develop a C-reactive protein-to-albumin ratio (CAR)-based nomogram for predicting the
risk of in-hospital death in sepsis patients. Sepsis patients were selected from the MIMIC-IV …

[HTML][HTML] Hepatoprotective, antioxidant, anti-inflammatory, and antiviral activities of silymarin against mayaro virus infection

AC Ferraz, LT Almeida, CC da Silva Caetano… - Antiviral Research, 2021 - Elsevier
Infection caused by Mayaro virus (MAYV) is responsible for causing acute nonspecific fever,
in which the majority of patients develop incapacitating and persistent arthritis/arthralgia …

Discovery of 4-oxo-N-phenyl-1, 4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis

J Yang, M Wang, Y Xu, J Liao, X Li, Y Zhou… - European Journal of …, 2023 - Elsevier
Acute lung injury (ALI) and sepsis, characterized by systemic inflammatory response
syndrome, remain the major causes of death in severe patients. Inhibiting the release of …

JQ1 as a BRD4 inhibitor blocks inflammatory pyroptosis-related acute colon injury induced by LPS

L Chen, X Zhong, W Cao, M Mao, W Li, H Yang… - Frontiers in …, 2021 - frontiersin.org
Endotoxemia is a severe inflammation response induced by infection especially bacterial
endotoxin translocation, which severely increases mortality in combination with acute colon …

[HTML][HTML] Matairesinol exerts anti-inflammatory and antioxidant effects in sepsis-mediated brain injury by repressing the MAPK and NF-κB pathways through up …

Q Wu, Y Wang, Q Li - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Brain injury is a familiar complication of severe sepsis, in which excessive inflammation and
oxidative stress are the main mechanisms leading to acute brain injury. Here, we focus on …