Hepatocellular carcinoma (HCC) is an aggressive disease with a poor clinical outcome. The
cancer stem cell (CSC) model states that tumour growth is powered by a subset of tumour …

Sustained hepatic inflammation is an important factor in progression of chronic liver
diseases, including hepatitis C or non-alcoholic steatohepatitis. Liver inflammation is …

Liver cancer is an aggressive disease with a poor outcome. Several hepatic stem/progenitor
markers are useful for isolating a subset of liver cells with stem cell features, known as …

Liver cancer is an often fatal malignant tumor with a high recurrence rate and
chemoresistance. The major malignant phenotypes of cancer, including recurrence …

Cancer stem cells (CSCs) or tumor initiating cells (TICs) contribute to tumorigenesis,
metastasis, recurrence and chemoresistance. CD133, a pentaspan membrane glycoprotein …

Objective Receptor-interacting protein kinase 3 (RIPK3) is a key player in necroptosis
execution and an emerging metabolic regulator, whose contribution to non-alcoholic fatty …

As one of the most abundant immune cell populations in the tumor microenvironment (TME),
tumor‐associated macrophages (TAMs) play important roles in multiple solid malignancies …

Liver cancer is the second most common cause of cancer-related death. The major forms of
primary liver cancer are hepatocellular carcinoma (HCC) and intrahepatic …

Inflammatory breast cancer (IBC) is a highly aggressive form of breast cancer that displays
profound cancer stem cell (CSC) and mesenchymal features that promote rapid metastasis …

Enhanced expression of the cancer stem cell (CSC) marker, CD133, is closely associated
with a higher rate of tumor formation and poor prognosis in hepatocellular carcinoma (HCC) …