Treatments for COVID-19

HS Andrews, JD Herman… - Annual Review of …, 2024 - annualreviews.org
The treatment for COVID-19 has evolved rapidly since the start of the pandemic and now
consists mainly of antiviral and immunomodulatory agents. Antivirals, such as remdesivir …

Diabetes mellitus, energy metabolism, and COVID-19

C Conte, E Cipponeri, M Roden - Endocrine Reviews, 2024 - academic.oup.com
Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Corticosteroids in COVID-19: pros and cons

A Bahsoun, Y Fakih, R Zareef, F Bitar, M Arabi - Frontiers in Medicine, 2023 - frontiersin.org
The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden
on the global healthcare sector. This necessitated a swift response from the international …

New clinical trial design in precision medicine: discovery, development and direction

XP Duan, BD Qin, XD Jiao, K Liu, Z Wang… - Signal Transduction and …, 2024 - nature.com
In the era of precision medicine, it has been increasingly recognized that individuals with a
certain disease are complex and different from each other. Due to the underestimation of the …

Clinical and electrocardiographic correlates of myocardial dysfunction after COVID‐19 in nonhospitalised patients in long‐term follow‐up. Data from the polish long …

J Kapusta, M Babicki… - Journal of Medical …, 2023 - Wiley Online Library
Clinical evidence indicates that COVID‐19 is a multiorgan disease that significantly impacts
the cardiovascular system. However, little is known about the predictors of myocardial …

Acellular Human Amniotic Fluid-Derived Extracellular Vesicles as Novel Anti-Inflammatory Therapeutics against SARS-CoV-2 Infection

D Chanda, T Del Rivero, R Ghimire, S More, MI Mitrani… - Viruses, 2024 - mdpi.com
The ongoing COVID-19 pandemic caused by SARS-CoV-2 is associated with acute
respiratory distress syndrome (ARDS) and fatal pneumonia. Excessive inflammation caused …

Effect of dexamethasone dose on outcomes in acute COVID-19 disease: A systematic review and meta-analysis

TAC Snow, N Arulkumaran, M Singer, C Sang-Ho - Journal of Infection, 2023 - Elsevier
Introduction The impact of different doses of dexamethasone on outcomes from acute
COVID-19 pneumonia is unknown. Methods We performed a systematic review and meta …

Association of fluvoxamine with mortality and symptom resolution among inpatients with COVID-19

G Zeng, J Li, L Wang, Z Zhang - Molecular Psychiatry, 2024 - nature.com
We have read with great interest the study by de Kirenga et al., about efficacy and safety of
fluvoxamine with mortality and symptom resolution among inpatients with COVID-19 [1] …

Real‐world effectiveness of Azvudine versus nirmatrelvir‐ritonavir in hospitalized patients with COVID‐19.

G Zeng, L Wang, J Li, Z Zhang - Journal of Medical Virology, 2023 - search.ebscohost.com
We have read with great interest the study by Deng et al.,[1] about Real-world effectiveness
of Azvudine versus nirmatrelvir-ritonavir in hospitalized patients with COVID-19. Previous …

Corticosteroids in adults with acute respiratory distress syndrome and severe pneumonia

D Jayasimhan, MA Matthay - BJA education, 2023 - bjaed.org
Discuss the pathogenesis of ARDS and the rationale for corticosteroid treatment. Evaluate
the evidence for the use of corticosteroids in specific subgroups of adults with ARDS. Apply …