Highly ordered clustering of TNFα and BAFF ligand-receptor-adaptor complexes bound to lipid membranes

CS Lim, J Lee, JW Kim, JO Lee - bioRxiv, 2024 - biorxiv.org
We report the cryo-EM structures of clusters of TNF receptor family proteins, TNFR1 and
BAFFR. The receptor-ligand complexes were anchored to a flat lipid layer to mimic the …