Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a
broad range of physiological and pathological processes. As a group, these proteins use …

Galectin-3 (Gal-3), a beta-galactoside-binding lectin, plays a pivotal role in various cellular
processes, including immune responses, inflammation, and cancer progression. This …

Abstract Purpose Galectin-3, a β-galactoside-binding lectin, plays a key role in several
cellular pathways involved in chronic inflammation, heart disease and cancer. GB1211 is an …

Purpose: Advances in our understanding of the contribution of aberrant glycosylation to the
pro-oncogenic signaling and metastasis of tumor cells have reinvigorated the development …

Changes in cell growth and metabolism are affected by the surrounding environmental
factors to adapt to the cell's most appropriate growth model. However, abnormal cell …

Abstract Galectin-3 (Gal-3), a multifunctional carbohydrate-binding lectin, has emerged as a
key player in various biological processes including inflammation, cancer, cardiovascular …

The Mucin (MUC) family, a range of highly glycosylated macromolecules, is ubiquitously
expressed in mammalian epithelial cells. Such molecules are pivotal in establishing …

Galectins play relevant roles in tumor development, progression and metastasis.
Accordingly, galectins are certainly enticing targets for medical intervention in cancer. To …

Galectin-3 is a member of the lectin family encoded by the LGALS3 gene on chromosome
14. It is secreted by a wide range of immune cells and mammary tumor cells. Through its …

Background Uterine serous cancer (USC) comprises around 10% of all uterine cancers.
However, USC accounts for approximately 40% of uterine cancer deaths, which is attributed …