[HTML][HTML] MAIT cells, guardians of skin and mucosa?

I Nel, L Bertrand, A Toubal, A Lehuen - Mucosal immunology, 2021 - Elsevier
Abstract Mucosal Associated Invariant T (MAIT) cells are evolutionary conserved innate-like
T cells able to recognize bacterial and fungal ligands derived from vitamin B biosynthesis …

Immunotherapy for colorectal cancer: mechanisms and predictive biomarkers

L Carlsen, KE Huntington, WS El-Deiry - Cancers, 2022 - mdpi.com
Simple Summary Late-stage colorectal cancer treatment often involves chemotherapy and
radiation that can cause dose-limiting toxicity, and therefore there is great interest in …

Mining the multifunction of mucosal-associated invariant T cells in hematological Malignancies and transplantation immunity: A promising hexagon soldier in …

MG Gao, XS Zhao - Frontiers in Immunology, 2022 - frontiersin.org
Mucosal-associated invariant T (MAIT) cells are evolutionarily conserved innate-like T cells
capable of recognizing bacterial and fungal ligands derived from vitamin B biosynthesis …

Time is ticking for cervical cancer

V Kumar, C Bauer, JH Stewart IV - Biology, 2023 - mdpi.com
Simple Summary Cervical cancer (CC) is a major health problem in women of childbearing
age. For example, CC is the fourth most common cancer in women across the world with an …

Mucosal-associated invariant T cells in cancer: dual roles, complex interactions and therapeutic potential

M Yigit, OF Basoglu, D Unutmaz - Frontiers in Immunology, 2024 - frontiersin.org
Mucosal-associated invariant T (MAIT) cells play diverse roles in cancer, infectious
diseases, and immunotherapy. This review explores their intricate involvement in cancer …

Remodelling of colorectal cancer cell signalling by microbiota and immunity in diabetes

M Gutiérrez-Salmerón, SR Lucena… - Endocrine-Related …, 2021 - erc.bioscientifica.com
Obesity is the strongest known risk factor to develop Type 2 diabetes (T2D) and both share a
state of chronic, diffuse and low-grade inflammation, impaired immune responses and …

[HTML][HTML] Ex Vivo Intestinal Organoid Models: Current State-of-the-Art and Challenges in Disease Modelling and Therapeutic Testing for Colorectal Cancer

S Randall-Demllo, G Al-Qadami, AE Raposo, C Ma… - Cancers, 2024 - mdpi.com
Despite improvements in participation in population-based screening programme, colorectal
cancer remains a major cause of cancer-related mortality worldwide. Targeted interventions …

Gut redox and microbiome: charting the roadmap to T-cell regulation

S Prasad, S Singh, S Menge, I Mohapatra… - Frontiers in …, 2024 - frontiersin.org
The gastrointestinal (GI) tract redox environment, influenced by commensal microbiota and
bacterial-derived metabolites, is crucial in shaping T-cell responses. Specifically …

Development of a monoclonal antibody to ITPRIPL1 for immunohistochemical diagnosis of non-small cell lung cancers: accuracy and correlation with CD8+ T cell …

S Deng, J Shi, Y Sun, Y Quan, Z Shen… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Cancer biomarkers are substances or processes highly associated with the
presence and progression of cancer, which are applicable for cancer screening, progression …

Cryopreservation of whole tumor biopsies from rectal cancer patients enable phenotypic and in vitro functional evaluation of tumor-infiltrating T cells

F Liang, A Rezapour, P Falk, E Angenete, U Yrlid - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer (CRC) remains the third most common malignancy.
Tumor-infiltrating lymphocytes (TILs) have emerged as correlates to CRC patient outcome …