Natural killer (NK) cells belong to the innate immune system and contribute to protecting the
host through killing of infected, foreign, stressed or transformed cells. Additionally, via …

While no single model can exactly recapitulate all aspects of multiple sclerosis (MS), animal
models are essential in understanding the induction and pathogenesis of the disease and to …

Autoimmune diseases generally result from the loss of self-tolerance (ie, failure of the
immune system to distinguish self from non-self), and are characterized by autoantibody …

Natural killer (NK) cells are powerful immune effectors whose antitumor activity is regulated
through a sophisticated network of activating and inhibitory receptors. As effectors of cancer …

Natural killer (NK) cells are large granular lymphocytes largely recognized for their
importance in tumour surveillance and the host response to viral infections. However, as the …

Human lung tissue-resident NK cells (trNK cells) are likely to play an important role in host
responses towards viral infections, inflammatory conditions and cancer. However, detailed …

Chemokines are small chemotactic molecules that play key roles in physiological and
pathological conditions. Upon signaling via their specific receptors, chemokines regulate …

Natural killer (NK) cells are traditionally considered as innate cells, but recent studies
suggest that NK cells can distinguish antigens, and that memory NK cells expand and …

Background & Aims CD26, a multifunctional transmembrane glycoprotein, is expressed in
various cancers and functions as dipeptidyl peptidase 4 (DPP4). We investigated whether …

As major components of innate immunity, NK cells not only exert cell-mediated cytotoxicity
against tumor cells or infected cells, but also act to regulate the function of other immune …