ContextThroughout the past 40 years, a vast and sometimes contradictory literature has
accumulated regarding hypertrophic cardiomyopathy (HCM), a genetic cardiac disease …

Writing Committee consisted of acknowledged experts in hypertrophic cardiomyopathy
(HCM) representing the American College of Cardiology Foundation and the European …

Background Sudden death is a possible consequence of hypertrophic cardiomyopathy.
Quantification of the risk of sudden death, however, remains imprecise for most patients with …

Hypertrophic cardiomyopathy is a common genetically transmitted disease, defined clinically
by the presence of unexplained left ventricular hypertrophy. The disease has a varied …

ContextHypertrophic cardiomyopathy (HCM) has been regarded as a disease that causes
substantial disability, with annual mortality rates of up to 6%, based largely on reports from …

Background: Diagnosis of cardiac ischaemia in patients attending emergency departments
(ED) with symptoms of acute coronary syndromes is often difficult. Cardiac troponin (cTn) is …

OBJECTIVES The purpose of this study was to determine whether the dynamic cause for
mitral systolic anterior motion (SAM) is a Venturi or a flow drag (pushing) mechanism …

Background—Percutaneous transluminal septal myocardial ablation (PTSMA) has been
introduced as an alternative procedure for reducing the left ventricular outflow tract gradient …

Background—The clinical efficacy of alcohol septal ablation for drug-refractory hypertrophic
cardiomyopathy remains unclear. This study examines the outcome of alcohol septal …

Emerging metabolomic tools have created the opportunity to establish metabolic signatures
of myocardial injury. We applied a mass spectrometry–based metabolite profiling platform to …