Abstract 22q11. 2 deletion syndrome (22q11. 2DS) is the most common chromosomal
microdeletion disorder, estimated to result mainly from de novo non-homologous meiotic …

Recent studies are beginning to paint a clear and consistent picture of the impairments in
psychological and cognitive competencies that are associated with microdeletions in …

Background—The goal of this statement was to review the available literature on
surveillance, screening, evaluation, and management strategies and put forward a scientific …

Arithmetic is still hugely important in many aspects of modern life, but our personal attitudes
to it differ greatly. Many people struggle with the basic principles of arithmetic, whilst others …

Autistic-spectrum conditions and psychotic-spectrum conditions (mainly schizophrenia,
bipolar disorder, and major depression) represent two major suites of disorders of human …

This review provides an overview of the involvement of the corpus callosum (CC) in a variety
of developmental disorders that are currently defined exclusively by genetics …

Evidence is rapidly accumulating that rare, recurrent copy number variants represent large
effect risk factors for neuropsychiatric disorders. 22q11. 2 deletion syndrome (22q11DS) …

Summary 22q11. 2 deletion carriers show specific cognitive deficits, and∼ 30% of them
develop schizophrenia. One of the disrupted genes is ZDHHC8, which encodes for a …

Genomic disorders are a group of human genetic diseases caused by genomic
rearrangements resulting in copy-number variation (CNV) affecting a dosage-sensitive gene …

Abstract Individuals with 22q11. 2 microdeletions have cognitive deficits and a high risk of
developing schizophrenia. Here we provide evidence that primary hippocampal neurons …