The current phase of drug development is witnessing an oncoming crisis due to the
combined effects of increasing R&D costs, decreasing number of new drug molecules being …

We present an experimental NMR, X-ray diffraction (XRD), and computational study of the
supramolecular assemblies of two crystalline forms of Ciprofloxacin: one anhydrate and one …

Pharmaceutical salt formation is the most preferred and effective method to enhance the
physicochemical properties of an active pharmaceutical ingredient (API) such as solubility …

Over the last years, resveratrol (RES), a phytoalexin found in grape skin, has received more
attention due to its properties antioxidant, anticancer, anti-inflammatory, antimicrobial and …

As the development of novel antibiotics has been at a halt for several decades, chemically
enhancing existing drugs is a very promising approach to drug development. Herein, we …

Ciprofloxacin (CIP) is a poorly soluble drug that also displays poor permeability. Attempts to
improve the solubility of this drug to date have largely focused on the formation of crystalline …

Bacterial biofilm and crystalline deposits are the common causes of failure of long-term
indwelling urinary catheter. Bacteria colonise the catheter surface causing serious infections …

The cocrystallization of the fluoroquinolones ciprofloxacin (cip), norfloxacin (nor), and
enrofloxacin (enro) with the α, ω-dicarboxylic acids glutaric acid (glu), adipic acid (adi) …

A cocrystallization tactic of double optimization and synergistic enhancement efficacy has
been proposed, aiming at maximizing the benefits of phenolic acid nutriment syringic acid …

New salts of antibiotic drug ciprofloxacin (CIP) with pharmaceutically acceptable maleic
(Mlt), fumaric (Fum) and adipic (Adp) acids were obtained and their crystal structures were …